Organelle biogenesis is concomitant to organelle inheritance during cell division. It is
necessary that organelles double their size and divide to give rise to two identical daughter …

Abstract The Free Radical Theory of Ageing, was first proposed by Denham Harman in the
mid-1950's, based largely on work conducted by Rebeca Gerschman and Daniel Gilbert. At …

Ageing causes loss of function in tissues and organs, is accompanied by a chronic
inflammatory process and affects life‐and healthspan. Calorie restriction (CR) is a non …

Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2
diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between …

Increased oxidative stress has been associated with the aging process. However, recent
studies have revealed that a low-level oxidative stress can even extend the lifespan of …

Antioxidant supplements for prevention of mortality in healthy participants and patients with
various diseases - Bjelakovic, G - 2012 | Cochrane Library Skip to Content Cookies Our site …

It has been 60 yr since the discovery of reactive oxygen species (ROS) in biology and the
beginning of the scientific community's attempt to understand the impact of the unpaired …

Abstract The superoxide anion (O2.−) is widely engaged in the regulation of cell functions
and is thereby intimately associated with the onset and progression of many diseases. To …

Aging is a degenerative, biological, time-dependent, universally conserved process thus
designed as one of the highest known risk factors for morbidity and mortality. Every …

Mitochondrial biogenesis is regulated to adapt mitochondrial population to cell energy
demands. Mitochondrial transcription factor A (TFAM) performs several functions for mtDNA …