Emergence of small interfering RNA-based gene drugs for various diseases

H Kurakula, S Vaishnavi, MY Sharif, S Ellipilli - ACS omega, 2023 - ACS Publications
Small molecule, peptide, and protein-based drugs have been developed over decades to
treat various diseases. The importance of gene therapy as an alternative to traditional drugs …

[HTML][HTML] Therapeutic agent-loaded fibrous scaffolds for biomedical applications

D Park, SJ Lee, DK Choi, JW Park - Pharmaceutics, 2023 - mdpi.com
Tissue engineering is a sophisticated field that involves the integration of various disciplines,
such as clinical medicine, material science, and life science, to repair or regenerate …

[HTML][HTML] Electrospun/3D-Printed bicomponent scaffold co-loaded with a prodrug and a drug with antibacterial and immunomodulatory properties

E Cojocaru, J Ghitman, GG Pircalabioru, A Zaharia… - Polymers, 2023 - mdpi.com
This work reports the construction of a bicomponent scaffold co-loaded with both a prodrug
and a drug (BiFp@ Ht) as an efficient platform for wound dressing, by combining the …

Innovative applications of electrospun nanofibers in cancer research

M Rasekh, F Pisapia, A Nokhodchi - Journal of Drug Delivery Science and …, 2024 - Elsevier
Cancer, a leading cause of global mortality, has ignited substantial interest in the
advancement of chemotherapy drugs. Nonetheless, challenges such as limited blood …

'Nano-in-nano'–Breaching the barriers of the tumor microenvironment using nanoparticle-incorporated nanofibers

G Pandey, S Shah, V Phatale, P Khairnar… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is one of the leading causes of death worldwide. Despite significant efforts and
advancements in cancer treatment, metastasis and tumor recurrence remain significant …

[HTML][HTML] Electrospun drug-loaded and gene-loaded nanofibres: the holy grail of glioblastoma therapy?

L Louis, BS Chee, M McAfee, M Nugent - Pharmaceutics, 2023 - mdpi.com
To date, GBM remains highly resistant to therapies that have shown promising effects in
other cancers. Therefore, the goal is to take down the shield that these tumours are using to …

[HTML][HTML] Advanced gene nanocarriers/scaffolds in nonviral-mediated delivery system for tissue regeneration and repair

W Zhang, Y Hou, S Yin, Q Miao, K Lee, X Zhou… - Journal of …, 2024 - Springer
Tissue regeneration technology has been rapidly developed and widely applied in tissue
engineering and repair. Compared with traditional approaches like surgical treatment, the …

[HTML][HTML] Fabrication of a PLA/PVA-BIO-HA Polymeric Membrane by the Electrospinning Technique

BL Arroyo-Reyes, CL Gómez-Muñoz, P Zaca-Morán… - Fibers, 2024 - mdpi.com
In the present work, the fabrication of a membrane composed of polylactic acid (PLA),
polyvinyl alcohol (PVA), and Biological Hydroxyapatite (BIO-HA) is reported using the …

Biodegradable Materials-Based Sensors

MA Abdelkawy, DM El-Sherif, GAM Ali - Handbook of Nanosensors …, 2024 - Springer
Biosensors have become an essential tool in a wide range of fields, from healthcare to
environmental monitoring. However, traditional biosensor substrates can be expensive, non …

8.1. 1 DESCRIPTION OF THE ELECTROSPINNING PROCESS

N Mats, PAM Chagas, GB Medeiros… - Electrospun …, 2023 - books.google.com
FIGURE 8.1 Traditional electrospinning apparatus using a flat plate as a collector. ranging
from 10 to 40 kV, between a charged syringe needle and a grounded metal plate collector. A …