[HTML][HTML] The MAPK Signaling Pathway Presents Novel Molecular Targets for Therapeutic Intervention after Traumatic Spinal Cord Injury: A Comparative Cross …

MM Zavvarian, C Zhou, S Kahnemuyipour… - International journal of …, 2021 - mdpi.com
Despite the debilitating consequences following traumatic spinal cord injury (SCI), there is a
lack of safe and effective therapeutics in the clinic. The species-specific responses to SCI …

[HTML][HTML] Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats

S Hashemizadeh, Z Gharaylou… - Frontiers in …, 2022 - frontiersin.org
Ion disturbances are among the most remarkable deficits in spinal cord injury (SCI). GABA is
an integral part of neural interaction. Action of the GABAA receptor depends on the amount …

[HTML][HTML] Peripheral nerve-derived stem cell spheroids induce functional recovery and repair after spinal cord injury in rodents

HL Lee, CE Yeum, HY Lee, J Oh, JT Kim… - International journal of …, 2021 - mdpi.com
Stem cell therapy is one of the most promising candidate treatments for spinal cord injury.
Research has shown optimistic results for this therapy, but clinical limitations remain …

Experimental treatments for spinal cord injury: what you should know

V Failli, N Kleitman, DP Lammertse… - Topics in spinal …, 2021 - meridian.allenpress.com
Experiencing a spinal cord injury (SCI) is extremely distressing, both physically and
psychologically, and throws people into a complex, unfamiliar world of medical procedures …

[HTML][HTML] The protein kinase inhibitor midostaurin improves functional neurological recovery and attenuates inflammatory changes following traumatic cervical spinal …

MM Zavvarian, J Hong, M Khazaei, JCT Chio, J Wang… - Biomolecules, 2021 - mdpi.com
Traumatic spinal cord injury (SCI) impairs neuronal function and introduces a complex
cascade of secondary pathologies that limit recovery. Despite decades of preclinical and …

Hesperidin guided injured spinal cord neural regeneration with a combination of MWCNT-collagen-hyaluronic acid composite: In-vitro analysis

M Raguraman, X Zhou, S Mickymaray… - International Journal of …, 2024 - Elsevier
Restoring the lost bioelectrical signal transmission along with the appropriate
microenvironment is one of the major clinical challenges in spinal cord regeneration. In the …

[HTML][HTML] Planet of the AAVs: the spinal cord injury episode

K Stepankova, P Jendelova, L Machova Urdzikova - Biomedicines, 2021 - mdpi.com
The spinal cord injury (SCI) is a medical and life-disrupting condition with devastating
consequences for the physical, social, and professional welfare of patients, and there is no …

[HTML][HTML] Translational Relevance of Secondary Intracellular Signaling Cascades Following Traumatic Spinal Cord Injury

MM Zavvarian, AD Modi, S Sadat, J Hong… - International Journal of …, 2024 - mdpi.com
Traumatic spinal cord injury (SCI) is a life-threatening and life-altering condition that results
in debilitating sensorimotor and autonomic impairments. Despite significant advances in the …

[HTML][HTML] The use of viral vectors to promote repair after spinal cord injury

A Islam, VJ Tom - Experimental neurology, 2022 - Elsevier
Spinal cord injury (SCI) is a devastating event that can permanently disrupt multiple
modalities. Unfortunately, the combination of the inhibitory environment at a central nervous …

基因疗法修复脊髓损伤: 临床前研究的系统综述和meta 分析

CJ Cunningham, M Viskontas, K Janowicz… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
Currently, there is no cure for traumatic spinal cord injury but one therapeutic approach
showing promise is gene therapy. In this systematic review and meta-analysis, we aim to …