Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

Epigenetic changes in DNA methylation contribute to the development of many diseases,
including cancer. In glioblastoma multiforme, the most prevalent primary brain cancer and …

Editorial expression of concern: In the May 2021 edition, the American Journal of
Neuroradilogy published the article “MRI-Based Deep-Learning Method for Determining …

Survival for glioma patients has shown minimal improvement over the past 20 years. The
ability to detect and monitor gliomas relies primarily upon imaging technologies that lack …

Gliomas are a heterogenous group of central nervous system tumors with different outcomes
and different therapeutic needs. Glioblastoma, the most common subtype in adults, has a …

Background Gliomas are the most common and aggressive tumors of the central nervous
system. A robust and widely used blood-based biomarker for glioma has not yet been …

Plant breeding conventionally depends on genetic variability available in a species to
improve a particular trait in the crop. However, epigenetic diversity may provide an …

Introduction Despite advances in modern medicine, brain tumor patients are still monitored
purely by clinical evaluation and imaging. Traditionally, invasive strategies such as open or …

Obtaining diagnostic specimens, notably to monitor disease course in cancer patients
undergoing therapy, is an emerging area of research, however, with few clinical implications …

Glioblastoma (GBM) is a highly malignant brain tumor with a dismal prognosis. Standard
therapy for GBM comprises surgical resection, followed by radiotherapy plus concomitant …