[HTML][HTML] Apathy as a treatment target in Alzheimer's disease: implications for clinical trials

ME Mortby, L Adler, L Agüera-Ortiz, DR Bateman… - The American Journal of …, 2022 - Elsevier
Apathy is one of the most prevalent, stable and persistent neuropsychiatric symptom across
the neurocognitive disorders spectrum. Recent advances in understanding of …

A systematic review of home-setting psychoeducation interventions for behavioral changes in dementia: some lessons for the COVID-19 pandemic and post-pandemic …

GS Alves, ME Casali, AB Veras, CG Carrilho… - Frontiers in …, 2020 - frontiersin.org
Background Impacts of social isolation measures imposed by COVID-19 Pandemic on
mental health and quality of life of older adults living with dementia and their caregivers …

Targeting behavioral symptoms and functional decline in dementia: a randomized clinical trial

LN Gitlin, P Arthur, C Piersol, V Hessels… - Journal of the …, 2018 - Wiley Online Library
Background/Objectives Dementia‐related behavioral symptoms and functional dependence
result in poor quality of life for persons with dementia and their caregivers. The goal was to …

An intervention to reduce neuropsychiatric symptoms and caregiver burden in dementia: P reliminary results from a randomized trial of the tailored activity program …

AM de Oliveira, M Radanovic… - … journal of geriatric …, 2019 - Wiley Online Library
Objective To evaluate the efficacy of the tailored activity program–outpatient version (TAP‐
O) and to reduce neuropsychiatric symptoms (NPS) in patients with dementia and caregiver …

A systematic review of non‐pharmacological treatments for apathy in dementia

C Theleritis, K Siarkos, AA Politis… - … Journal of Geriatric …, 2018 - Wiley Online Library
Objective Apathy is one of the most frequent neuropsychiatric symptoms encountered in
dementia. Early diagnosis and timely treatment of apathy in dementia are crucial because …

Effects of the tailored activity program (TAP) on dementia-related symptoms, health events and caregiver wellbeing: a randomized controlled trial

LN Gitlin, K Marx, CV Piersol, NA Hodgson, J Huang… - BMC geriatrics, 2021 - Springer
Background People living with dementia (PLWD) and caregivers are adversely impacted by
lack of meaningful activity leading to worse symptoms and impaired quality-of-life. There is a …

Rehabilitation to live better with dementia

Y Maki, T Sakurai, J Okochi… - Geriatrics & …, 2018 - Wiley Online Library
The goal of dementia treatment is to improve the quality of life for both people with dementia
and their families. Rehabilitation as a non‐pharmacological approach, coordinated with …

Telephone interventions, delivered by healthcare professionals, for providing education and psychosocial support for informal caregivers of adults with diagnosed …

M Corry, K Neenan, S Brabyn… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Maintaining care for ill persons in the community is heavily dependent on
support from unpaid caregivers. Many caregivers, however, find themselves in a caring role …

Pharmacological and Nonpharmacological Treatment for Apathy in Alzheimer Disease: A systematic review across modalities

C Theleritis, K Siarkos… - Journal of geriatric …, 2017 - journals.sagepub.com
Objective: Apathy is one of the most frequent neuropsychiatric symptoms encountered in
Alzheimer disease (AD). Early diagnosis and timely treatment of apathy in AD seem to be of …

The tailored activity program (TAP) to address behavioral disturbances in frontotemporal dementia: a feasibility and pilot study

CM O'Connor, L Clemson, H Brodaty… - Disability and …, 2019 - Taylor & Francis
Purpose: To explore the feasibility of implementing the Tailored Activity Program with a
cohort of people with frontotemporal dementia and their carers (dyads). Methods: The …