The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …

Involvement of small airways, those of< 2 mm in internal diameter, is present in all stages of
asthma and contributes substantially to its pathophysiologic expression. Therefore, small …

The purpose of this study is to design a flower‐shaped lactose loaded curcumin solid lipid
nanoparticles dry powder inhaler and characterize it to improve the solubility and dissolution …

Asthma is a chronic disease, affecting approximately 350 million people worldwide.
Inflammation and remodeling in asthma involve the large airways, and it is now widely …

Background In asthma, inflammation affects both the proximal and distal airways and can
cause significant hyperinflation, which is thought to be a major cause of dyspnea. Methods …

Asthma is a common chronic condition, affecting approximately 339 million people
worldwide. The main goal of the current asthma treatment guidelines is to achieve clinical …

In people with COPD, pulmonary gas-exchange efficiency may be impaired because of
abnormal alveolar ventilation (V˙ A), capillary perfusion (Q˙ c), or both. Both have been …

Introduction Small airway disease (SAD) represents a common and critical feature of
Chronic Obstructive Pulmonary Disease (COPD). Introduced in the'60s, SAD has gradually …

Chronic obstructive pulmonary disease (COPD) is a chronic airway inflammatory disease
characterized by incomplete reversible airflow limitation. The diagnosis of COPD is mainly …

Airway epithelial damage is a common feature in respiratory diseases such as COPD and
has been suggested to drive inflammation and progression of disease. These features …