Hypervirulent klebsiella pneumoniae

TA Russo, CM Marr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than
classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are …

Pseudomonas aeruginosa and Klebsiella pneumoniae adaptation to innate immune clearance mechanisms in the lung

SA Riquelme, D Ahn, A Prince - Journal of innate immunity, 2018 - karger.com
Many different species of gram-negative bacteria are associated with infection in the lung,
causing exacerbations of chronic obstructive pulmonary disease, cystic fibrosis (CF), and …

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

KL Wyres, RR Wick, LM Judd, R Froumine… - PLoS …, 2019 - journals.plos.org
Klebsiella pneumoniae has emerged as an important cause of two distinct public health
threats: multi-drug resistant (MDR) healthcare-associated infections and drug susceptible …

Evolution of hypervirulence in carbapenem-resistant Klebsiella pneumoniae in China: a multicentre, molecular epidemiological analysis

Y Zhang, L Jin, P Ouyang, Q Wang… - Journal of …, 2020 - academic.oup.com
Abstract Objectives Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP)
have been increasingly reported in China. Here, a multicentre, longitudinal surveillance …

[HTML][HTML] Novel subclone of carbapenem-resistant Klebsiella pneumoniae sequence type 11 with enhanced virulence and transmissibility, China

K Zhou, T Xiao, S David, Q Wang, Y Zhou… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
We aimed to clarify the epidemiologic and clinical importance of evolutionary events that
occurred in carbapenem-resistant Klebsiella pneumoniae (CRKP). We collected 203 CRKP …

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

KL Wyres, TNT Nguyen, MMC Lam, LM Judd… - Genome medicine, 2020 - Springer
Background Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI).
Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are …

Hypervirulent Klebsiella pneumoniae is emerging as an increasingly prevalent K. pneumoniae pathotype responsible for nosocomial and healthcare-associated …

C Liu, P Du, N Xiao, F Ji, TA Russo, J Guo - Virulence, 2020 - Taylor & Francis
ABSTRACT Objectives Hypervirulent Klebsiella pneumoniae (hvKp) is an increasingly
important pathogen. Tracking its epidemiology and evolving antimicrobial resistance will …

Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae

MMC Lam, KL Wyres, LM Judd, RR Wick, A Jenney… - Genome medicine, 2018 - Springer
Background Klebsiella pneumoniae is a recognised agent of multidrug-resistant (MDR)
healthcare-associated infections; however, individual strains vary in their virulence potential …

Comprehensive Genomic Investigation of Tigecycline Resistance Gene tet(X4)-Bearing Strains Expanding among Different Settings

R Li, Y Li, K Peng, Y Yin, Y Liu, T He, L Bai… - Microbiology …, 2021 - Am Soc Microbiol
The emergence of plasmid-mediated tigecycline resistance genes has attracted a great deal
of attention globally. Currently, no comprehensive in-depth genomic epidemiology study of …

Tracking microevolution events among ST11 carbapenemase-producing hypervirulent Klebsiella pneumoniae outbreak strains

N Dong, X Yang, R Zhang, EWC Chan… - Emerging microbes & …, 2018 - Taylor & Francis
The recent convergence of genetic elements encoding phenotypic carbapenem-resistance
and hypervirulence within a single Klebsiella pneumoniae host strain represents a major …