Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Emerging Burden

S Batool, K Morton Cuthrell, N Tzenios… - … Research Journal of …, 2022 - publish7promo.com
Liver is the largest solid organ in the body that performs over 100 functions. It removes the
toxins and waste products from the blood stream, maintains healthy blood sugar levels …

Etiology of hepatocellular carcinoma: special focus on fatty liver disease

D Suresh, AN Srinivas, DP Kumar - Frontiers in Oncology, 2020 - frontiersin.org
Hepatocellular Carcinoma (HCC) is a highly aggressive cancer with mortality running
parallel to its incidence and has limited therapeutic options. Chronic liver inflammation and …

Organoid models of gastrointestinal cancers in basic and translational research

HCH Lau, O Kranenburg, H Xiao, J Yu - … reviews Gastroenterology & …, 2020 - nature.com
Cancer is a major public health problem worldwide. Gastrointestinal cancers account for
approximately one-third of the total global cancer incidence and mortality. Historically, the …

Therapeutic options in hepatocellular carcinoma: a comprehensive review

D Suresh, AN Srinivas, A Prashant… - Clinical and …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a chronic liver disease that is highly fatal if not detected
and treated early. The incidence and death rate of HCC have been increasing in recent …

The emerging role of metformin in the treatment of hepatocellular carcinoma: is there any value in repurposing metformin for HCC immunotherapy?

SP Papadakos, D Ferraro, G Carbone, AE Frampton… - Cancers, 2023 - mdpi.com
Simple Summary The study investigates the potential use of metformin, a medication
commonly prescribed for type 2 diabetes, in the treatment of hepatocellular carcinoma …

Optimizing survival and the changing landscape of targeted therapy for intermediate and advanced hepatocellular carcinoma: a systematic review

H Lim, R Ramjeesingh, D Liu, VC Tam… - JNCI: Journal of the …, 2021 - academic.oup.com
Background: Systemic therapy for hepatocellular carcinoma (HCC) consisting of the tyrosine
kinase inhibitor sorafenib has remained unchanged for over a decade, although results from …

Real-world use of immunotherapy for hepatocellular carcinoma

A Sara, SM Ruff, AM Noonan… - Pragmatic and …, 2023 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality
worldwide and accounts for 90% of all primary liver cancers. Chronic inflammation is the …

Multiple roles of LOXL2 in the progression of hepatocellular carcinoma and its potential for therapeutic targeting

J Radić, B Kožik, I Nikolić, I Kolarov-Bjelobrk… - International Journal of …, 2023 - mdpi.com
LOXL2, a copper-dependent amine oxidase, has emerged as a promising therapeutic target
in hepatocellular carcinoma (HCC). Increased LOXL2 expression in HCC has been linked …

KIF2C promotes the proliferation of hepatocellular carcinoma cells in vitro and in vivo Retraction in /10.3892/etm.2023.12095

Z Gao, H Jia, F Yu, H Guo, B Li - Experimental and …, 2021 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignancies with high
mortality and morbidity rates. In recent years, HCC targeted therapy has gained increasing …

Selection of a clinical lead TCR targeting alpha-fetoprotein-positive liver cancer based on a balance of risk and benefit

X Luo, H Cui, L Cai, W Zhu, WC Yang… - Frontiers in …, 2020 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with a
poor prognosis and limited therapeutic options. Alpha-fetoprotein (AFP), an established …