[HTML][HTML] Mechanisms of multidrug resistance in cancer chemotherapy
K Bukowski, M Kciuk, R Kontek - International journal of molecular …, 2020 - mdpi.com
Cancer is one of the main causes of death worldwide. Despite the significant development of
methods of cancer healing during the past decades, chemotherapy still remains the main …
methods of cancer healing during the past decades, chemotherapy still remains the main …
[HTML][HTML] Tumor-associated macrophages: an accomplice in solid tumor progression
Y Chen, Y Song, W Du, L Gong, H Chang… - Journal of biomedical …, 2019 - Springer
In many solid tumor types, tumor-associated macrophages (TAMs) are important
components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly …
components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly …
Induction of reactive oxygen species: an emerging approach for cancer therapy
Z Zou, H Chang, H Li, S Wang - Apoptosis, 2017 - Springer
Reactive oxygen species (ROS), a group of ions and molecules, include hydroxyl radicals (·
OH), alkoxyl radicals, superoxide anion (O 2·−), singlet oxygen (1 O 2) and hydrogen …
OH), alkoxyl radicals, superoxide anion (O 2·−), singlet oxygen (1 O 2) and hydrogen …
[HTML][HTML] Targeted therapy and mechanisms of drug resistance in breast cancer
Simple Summary Internationally, in women, breast cancer (BC) is the most common cancer
type and is the leading cause of cancer-related death. There are two main histological …
type and is the leading cause of cancer-related death. There are two main histological …
[HTML][HTML] miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study
BN Hannafon, A Cai, CL Calloway, YF Xu, R Zhang… - BMC cancer, 2019 - Springer
Background Altered expression of microRNAs (miRNAs) is known to contribute to cancer
progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported …
progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported …
The orphan nuclear receptors steroidogenic factor-1 and liver receptor homolog-1: structure, regulation, and essential roles in mammalian reproduction
MC Meinsohn, OE Smith, K Bertolin… - Physiological …, 2019 - journals.physiology.org
Nuclear receptors are intracellular proteins that act as transcription factors. Proteins with
classic nuclear receptor domain structure lacking identified signaling ligands are designated …
classic nuclear receptor domain structure lacking identified signaling ligands are designated …
[HTML][HTML] miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells
D Chen, W Si, J Shen, C Du, W Lou, C Bao… - Cell death & …, 2018 - nature.com
Drug resistance remains a major problem in the treatment of conventional chemotherapeutic
agents in breast cancers. Owing to heterogeneity and complexity of chemoresistance …
agents in breast cancers. Owing to heterogeneity and complexity of chemoresistance …
[HTML][HTML] The network of non-coding RNAs in cancer drug resistance
F Corrà, C Agnoletto, L Minotti, F Baldassari… - Frontiers in …, 2018 - frontiersin.org
Non-coding RNAs (ncRNAs) have been implicated in most cellular functions. The disruption
of their function through somatic mutations, genomic imprinting, transcriptional and post …
of their function through somatic mutations, genomic imprinting, transcriptional and post …
[HTML][HTML] Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer
W Wang, L Zhang, Y Wang, Y Ding, T Chen… - Cell death & …, 2017 - nature.com
MicroRNAs (miRNAs) have been identified as major post-transcriptional regulators of the
initiation and progression of human cancers, including breast cancer. However, the detail …
initiation and progression of human cancers, including breast cancer. However, the detail …
MicroRNA-27b modulates inflammatory response and apoptosis during Mycobacterium tuberculosis infection
S Liang, Z Song, Y Wu, Y Gao, M Gao, F Liu… - The Journal of …, 2018 - journals.aai.org
Mycobacterium tuberculosis poses a significant global health threat. MicroRNAs play an
important role in regulating host anti-mycobacterial defense; however, their role in apoptosis …
important role in regulating host anti-mycobacterial defense; however, their role in apoptosis …