[HTML][HTML] Mechanisms of multidrug resistance in cancer chemotherapy

K Bukowski, M Kciuk, R Kontek - International journal of molecular …, 2020 - mdpi.com
Cancer is one of the main causes of death worldwide. Despite the significant development of
methods of cancer healing during the past decades, chemotherapy still remains the main …

[HTML][HTML] Tumor-associated macrophages: an accomplice in solid tumor progression

Y Chen, Y Song, W Du, L Gong, H Chang… - Journal of biomedical …, 2019 - Springer
In many solid tumor types, tumor-associated macrophages (TAMs) are important
components of the tumor microenvironment (TME). Moreover, TAMs infiltration is strongly …

Induction of reactive oxygen species: an emerging approach for cancer therapy

Z Zou, H Chang, H Li, S Wang - Apoptosis, 2017 - Springer
Reactive oxygen species (ROS), a group of ions and molecules, include hydroxyl radicals (·
OH), alkoxyl radicals, superoxide anion (O 2·−), singlet oxygen (1 O 2) and hydrogen …

[HTML][HTML] Targeted therapy and mechanisms of drug resistance in breast cancer

B Kinnel, SK Singh, G Oprea-Ilies, R Singh - Cancers, 2023 - mdpi.com
Simple Summary Internationally, in women, breast cancer (BC) is the most common cancer
type and is the leading cause of cancer-related death. There are two main histological …

[HTML][HTML] miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study

BN Hannafon, A Cai, CL Calloway, YF Xu, R Zhang… - BMC cancer, 2019 - Springer
Background Altered expression of microRNAs (miRNAs) is known to contribute to cancer
progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported …

The orphan nuclear receptors steroidogenic factor-1 and liver receptor homolog-1: structure, regulation, and essential roles in mammalian reproduction

MC Meinsohn, OE Smith, K Bertolin… - Physiological …, 2019 - journals.physiology.org
Nuclear receptors are intracellular proteins that act as transcription factors. Proteins with
classic nuclear receptor domain structure lacking identified signaling ligands are designated …

[HTML][HTML] miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells

D Chen, W Si, J Shen, C Du, W Lou, C Bao… - Cell death & …, 2018 - nature.com
Drug resistance remains a major problem in the treatment of conventional chemotherapeutic
agents in breast cancers. Owing to heterogeneity and complexity of chemoresistance …

[HTML][HTML] The network of non-coding RNAs in cancer drug resistance

F Corrà, C Agnoletto, L Minotti, F Baldassari… - Frontiers in …, 2018 - frontiersin.org
Non-coding RNAs (ncRNAs) have been implicated in most cellular functions. The disruption
of their function through somatic mutations, genomic imprinting, transcriptional and post …

[HTML][HTML] Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer

W Wang, L Zhang, Y Wang, Y Ding, T Chen… - Cell death & …, 2017 - nature.com
MicroRNAs (miRNAs) have been identified as major post-transcriptional regulators of the
initiation and progression of human cancers, including breast cancer. However, the detail …

MicroRNA-27b modulates inflammatory response and apoptosis during Mycobacterium tuberculosis infection

S Liang, Z Song, Y Wu, Y Gao, M Gao, F Liu… - The Journal of …, 2018 - journals.aai.org
Mycobacterium tuberculosis poses a significant global health threat. MicroRNAs play an
important role in regulating host anti-mycobacterial defense; however, their role in apoptosis …