1, 4-Dihydropyridines as calcium channel ligands and privileged structures
DJ Triggle - Cellular and molecular neurobiology, 2003 - Springer
The 1, 4-dihydropyridine nucleus serves as the scaffold for important cardiovascular drugs—
calcium antagonists—including nifedipine, nitrendipine, amlodipine, and nisoldipine, which …
calcium antagonists—including nifedipine, nitrendipine, amlodipine, and nisoldipine, which …
Recent progresses in the multicomponent synthesis of dihydropyridines by applying sustainable catalysts under green conditions
The synthesis of dihydropyridines, valuable molecules with diverse therapeutic properties,
using eco-friendly heterogeneous catalysts as a green alternative received significant …
using eco-friendly heterogeneous catalysts as a green alternative received significant …
L-type calcium channel blockers: a potential novel therapeutic approach to drug dependence
HJ Little - Pharmacological Reviews, 2021 - ASPET
This review describes interactions between compounds, primarily dihydropyridines, that
block L-type calcium channels and drugs that cause dependence, and the potential …
block L-type calcium channels and drugs that cause dependence, and the potential …
L-type calcium channels
DJ Triggle - Current pharmaceutical design, 2006 - ingentaconnect.com
The Ca2+ channel blockers represent a successful group of therapeutic agents directed
against cardiovascular targets, including hypertension and angina. These drugs, including …
against cardiovascular targets, including hypertension and angina. These drugs, including …
Alginic acid: a highly efficient renewable and heterogeneous biopolymeric catalyst for one-pot synthesis of the Hantzsch 1, 4-dihydropyridines
Alginic acid, a naturally occurring polysaccharide, in its granular form and without any post-
modification was found to be an efficient, environmentally benign, easily recoverable and …
modification was found to be an efficient, environmentally benign, easily recoverable and …
Interaction between felodipine and bovine serum albumin: fluorescence quenching study
US Mote, SL Bhattar, SR Patil, GB Kolekar - Luminescence, 2010 - Wiley Online Library
The fluorescence quenching spectrum of bovine serum albumin (BSA) was investigated in
the presence of felodipine (FLD) by spectroscopic methods including fluorescence …
the presence of felodipine (FLD) by spectroscopic methods including fluorescence …
H5BW12O40-Catalyzed syntheses of 1, 4-dihydropyridines and polyhydroquinolines via Hantzsch reaction: Joint experimental and computational studies
T Momeni, MM Heravi, T Hosseinnejad… - Journal of Molecular …, 2020 - Elsevier
A series of polyhydroquinoline derivatives were effectively synthesized via Hantzsch
reaction in high yields in the presence of catalytic amounts of a highly negatively charged …
reaction in high yields in the presence of catalytic amounts of a highly negatively charged …
Synthesis and evaluation of 1, 4-dihydropyridine derivatives with calcium channel blocking activity
Dihydropyridines (DHPs) are an important class of L-type calcium channel blockers that are
used to treat conditions such as hypertension and angina. Their primary target in the …
used to treat conditions such as hypertension and angina. Their primary target in the …
Synthesis and application of chitosan supported vanadium oxo in the synthesis of 1, 4-dihydropyridines and 2, 4, 6-triarylpyridines via anomeric based oxidation
M Safaiee, B Ebrahimghasri, MA Zolfigol… - New Journal of …, 2018 - pubs.rsc.org
Chitosan, as a biopolymer, exhibits a strong affinity for complexation with suitable metal
ions. Thus, it has received increased attention for the preparation of stable bioorganic …
ions. Thus, it has received increased attention for the preparation of stable bioorganic …
[HTML][HTML] The calcium channel inhibitor lacidipine inhibits Zika virus replication in neural progenitor cells
B Bezemer, KWR van Cleef, GJ Overheul, P Miesen… - Antiviral Research, 2022 - Elsevier
After decades of being considered non-pathogenic, Zika virus (ZIKV) emerged as an
important threat to human health during the epidemic of 2015–2016. ZIKV infections are …
important threat to human health during the epidemic of 2015–2016. ZIKV infections are …