Genetic incompatibility of the reproductive partners: an evolutionary perspective on infertility

J Kekäläinen - Human Reproduction, 2021 - academic.oup.com
In natural fertilisation, the female reproductive tract allows only a strictly selected sperm
subpopulation to proceed in the vicinity of an unfertilised oocyte. Female-mediated sperm …

Cryptic female choice within individual males–A neglected component of the postmating sexual selection?

J Kekäläinen - Journal of Evolutionary Biology, 2022 - academic.oup.com
Cryptic female choice (CFC) is commonly assumed to act only in polyandrous mating
systems, which allows females to bias fertilization towards the sperm of particular males …

Effect of MHC and inbreeding on disassortative reproduction: A data revisit, extension and inclusion of fertilization in sand lizards

B Bererhi, P Duchesne, TS Schwartz… - Ecology and …, 2023 - Wiley Online Library
The harmful effects of close inbreeding have been recognized for centuries and, with the rise
of Mendelian genetics, was realized to be an effect of homozygosis. This historical …

Metabolic syndrome and male fertility disorders: Is there a causal link?

DJ Cohen, MM Giaccagli, JD Herzfeld… - Reviews in Endocrine …, 2021 - Springer
Infertility is a global health problem affecting 10–15% of couples in reproductive age. Recent
studies have provided growing evidence supporting that lifestyle factors can affect male …

Unravelling the genetics of non-random fertilization associated with gametic incompatibility

AAA Martin, S Id-Lahoucine, PAS Fonseca… - Scientific reports, 2022 - nature.com
In the dairy industry, mate allocation is dependent on the producer's breeding goals and the
parents' breeding values. The probability of pregnancy differs among sire-dam …

Female‐induced selective modification of sperm protein SUMOylation—potential mechanistic insights into the non‐random fertilization in humans

J Kekäläinen, J Hiltunen, A Jokiniemi… - Journal of …, 2022 - academic.oup.com
In many species, mate choice continues after the mating via female‐or egg‐derived
biochemical factors that induce selective changes in sperm pre‐fertilization physiology and …

Structural dissimilarity of partners' immune genes increases sperm viability in women's reproductive tract

M Magris, A Jokiniemi, L Kuusipalo… - Journal of …, 2021 - academic.oup.com
Human leucocyte antigen (HLA) genes appear to mediate pre‐and post‐copulatory mate
choice towards HLA‐dissimilar ('compatible') partners. However, since genetically distinct …

Sperm Physiological Response to Female Serum—Potential New Insights into the Reproductive Incompatibility Diagnostics

A Łukasiewicz, K Huhta, J Ritari, J Peräsaari… - International Journal of …, 2022 - mdpi.com
Infertility is assumed to arise exclusively from male-and female-dependent pathological
factors. However, recent studies have indicated that reproductive failure may also result from …

Female reed warblers in social pairs with low MHC dissimilarity achieve higher MHC compatibility through random extra-pair matings

L Halupka, E O'Connor, M Strandh, H Sztwiertnia… - bioRxiv, 2023 - biorxiv.org
Abstract Major Histocompatibility Complex (MHC) polymorphism is maintained by balancing
selection through host-pathogen interactions and mate choice. MHC-based mate choice has …

Infertility: a pathologic condition or selection against genetic incompatibility?

J Kekäläinen - Global Reproductive Health, 2022 - journals.lww.com
Infertility is currently regarded as a male or female-dependent pathologic condition.
However, emerging evidence suggests that this may be an incomplete view as it misses the …