Physical exercise, such as forced treadmill running and swimming, can sufficiently improve
mechanical allodynia and heat hyperalgesia in animal models of neuropathic pain (NPP) …

Due to the chemical structural diversity and various analgesic mechanisms, an increasing
number of studies indicated that some flavonoids from medicinal plants could be promising …

The traditional Japanese herbal medicine hangeshashinto (HST) has beneficial effects for
the treatment of oral ulcerative mucositis (OUM) in cancer patients. However, the ingredient …

Despite the intense research on developing new therapies for neuropathic pain states,
available treatments have limited efficacy and unfavorable safety profiles. Epigenetic …

Neuropathic pain (NP) is the result of irregular processing in the central or peripheral
nervous system, which is generally caused by neuronal injury. The management of NP …

Introduction: Current pharmacotherapeutics for neuropathic pain offer only symptomatic
relief without treating the underlying pathophysiology. Additionally, they are associated with …

Neuropathic pain (NP) is a chronic disease that affects the normal quality of life of patients.
To date, the therapies available are only symptomatic and they are unable to reduce the …

Physical exercise has been established as a low-cost, safe, and effective way to manage
chronic intractable pain. We investigated the underlying mechanisms of exercise-induced …

Purpose Precision pain medicine focuses on employing methods to assess each patient
individually, identify their risk profile for disproportionate pain and/or the development of …

Physical exercise can attenuate neuropathic pain (NPP), but the exact mechanism
underlying exercise-induced hypoalgesia (EIH) remains unclear. Recent studies have …