The four epidemiological stages in the global evolution of inflammatory bowel disease

GG Kaplan, JW Windsor - Nature reviews Gastroenterology & …, 2021 - nature.com
Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four
epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence …

Mucins in intestinal mucosal defense and inflammation: learning from clinical and experimental studies

JA Grondin, YH Kwon, PM Far, S Haq… - Frontiers in …, 2020 - frontiersin.org
Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly
glycosylated proteins called mucins plays an essential role in providing lubrication for the …

How autophagy controls the intestinal epithelial barrier

EG Foerster, T Mukherjee, L Cabral-Fernandes… - Autophagy, 2022 - Taylor & Francis
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-
mediated recycling of organelles and protein aggregates, as well as the destruction of …

Clinical effects and gut microbiota changes of using probiotics, prebiotics or synbiotics in inflammatory bowel disease: A systematic review and meta-analysis

XF Zhang, XX Guan, YJ Tang, JF Sun, XK Wang… - European journal of …, 2021 - Springer
Purpose Probiotics have been reported to be beneficial for inflammatory bowel disease
(IBD), but the types, number of strains, dosage, and intervention time of probiotics used …

Genetic and epigenetic etiology of inflammatory bowel disease: An update

S Jarmakiewicz-Czaja, M Zielińska, A Sokal, R Filip - Genes, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and
remission of the disease. The etiology of IBD is not fully understood. Many studies point to …

Disturbances of the gut microbiota and microbiota-derived metabolites in inflammatory bowel disease

Y Hu, Z Chen, C Xu, S Kan, D Chen - Nutrients, 2022 - mdpi.com
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is characterized as a chronic and recurrent inflammatory disease whose pathogenesis …

Natural anti-inflammatory compounds as drug candidates for inflammatory bowel disease

L Duan, S Cheng, L Li, Y Liu, D Wang… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

Ulcerative colitis: understanding its cellular pathology could provide insights into novel therapies

A Kaur, P Goggolidou - Journal of inflammation, 2020 - Springer
Dynamic interactions between the gastrointestinal epithelium and the mucosal immune
system normally contribute to ensuring intestinal homeostasis and optimal …

Therapeutic effect of baicalin on inflammatory bowel disease: A review

X Wang, L Xie, J Long, K Liu, J Lu, Y Liang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Baicalin (BI) is an important biologically active flavonoid
isolated from the root of Scutellaria radix (Huang Qin). Traditionally Scutellaria radix was the …

Iron deficiency anemia in inflammatory bowel diseases—a narrative review

D Mahadea, E Adamczewska, AE Ratajczak… - Nutrients, 2021 - mdpi.com
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is
characterized by chronic inflammation of the gastrointestinal tract. IBD has been associated …