Copy number variants (CNVs) are intermediate-scale structural variants containing copy
number changes involving DNA fragments of between 1 kb and 5 Mb. Although known to …

The invention provides improved methods, compositions, and kits for detecting ploidy of
chromosome regions, eg for detecting cancer or a chromosomal abnormality in a gestating …

The clinical, pathologic, and molecular features of pleomorphic lobular carcinoma in situ
(PLCIS) and the relationship of PLCIS to classic LCIS (CLCIS) are poorly defined. In this …

▪ Abstract DNA microarray technology is revolutionizing many aspects of biological research,
allowing the expression of many thousands of gene transcripts to be monitored …

Changepoint detection methods are used in many areas of science and engineering, for
example, in the analysis of copy number variation data to detect abnormalities in copy …

We have used array comparative genomic hybridization to map DNA copy–number changes
in 94 patients with cri du chat syndrome who had been carefully evaluated for the presence …

Giant cell tumor of bone (GCT) is a generally benign, osteolytic neoplasm comprising
stromal cells and osteoclast-like giant cells. The osteoclastic cells, which cause bony …

US10011870B2 - Compositions and methods for identifying nucleic acid molecules - Google
Patents US10011870B2 - Compositions and methods for identifying nucleic acid molecules …

US10577650B2 - Compositions and methods for identifying nucleic acid molecules - Google
Patents US10577650B2 - Compositions and methods for identifying nucleic acid molecules …

Purpose Array comparative genomic hybridization is rapidly becoming an integral part of
cytogenetic diagnostics. We report the design, validation, and clinical utility of an …