Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
C Mestre-Escorihuela, F Rubio-Moscardo, JA Richter… - Blood, 2007 - ashpublications.org
Integrative genomic and gene-expression analyses have identified amplified oncogenes in
B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize …
B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize …
Application of array-based comparative genomic hybridization to clinical diagnostics
BA Bejjani, LG Shaffer - The Journal of Molecular Diagnostics, 2006 - Elsevier
Microarray-based comparative genomic hybridization (array CGH) is a revolutionary
platform that was recently adopted in the clinical laboratory. This technology was first …
platform that was recently adopted in the clinical laboratory. This technology was first …
Using high-density DNA methylation arrays to profile copy number alterations
The integration of genomic and epigenomic data is an increasingly popular approach for
studying the complex mechanisms driving cancer development. We have developed a …
studying the complex mechanisms driving cancer development. We have developed a …
Angiogenesis-independent tumor growth mediated by stem-like cancer cells
PØ Sakariassen, L Prestegarden… - Proceedings of the …, 2006 - National Acad Sciences
In this work, highly infiltrative brain tumors with a stem-like phenotype were established by
xenotransplantation of human brain tumors in immunodeficient nude rats. These tumors …
xenotransplantation of human brain tumors in immunodeficient nude rats. These tumors …
Comparative genomic hybridization
D Pinkel, DG Albertson - Annu. Rev. Genomics Hum. Genet., 2005 - annualreviews.org
▪ Abstract Altering DNA copy number is one of the many ways that gene expression and
function may be modified. Some variations are found among normal individuals (,,), others …
function may be modified. Some variations are found among normal individuals (,,), others …
Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes
F Rubio-Moscardo, D Blesa, C Mestre, R Siebert… - Blood, 2005 - ashpublications.org
Deletions of chromosome 8p are a recurrent event in B-cell non-Hodgkin lymphoma (B-
NHL), suggesting the presence of a tumor suppressor gene. We have characterized these …
NHL), suggesting the presence of a tumor suppressor gene. We have characterized these …
Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes
TM Kim, R Xi, LJ Luquette, RW Park… - Genome …, 2013 - genome.cshlp.org
A large database of copy number profiles from cancer genomes can facilitate the
identification of recurrent chromosomal alterations that often contain key cancer-related …
identification of recurrent chromosomal alterations that often contain key cancer-related …
Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations
JA Martinez-Climent, AA Alizadeh… - Blood, The Journal …, 2003 - ashpublications.org
Genomic aberrations in a series of paired biopsy samples from patients who presented
initially with follicle center lymphoma (FCL) and subsequently transformed to diffuse large B …
initially with follicle center lymphoma (FCL) and subsequently transformed to diffuse large B …
Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies
Natural killer (NK)-cell malignancies are among the most aggressive lymphoid neoplasms
with very poor prognosis. We performed array comparative genomic hybridization analysis …
with very poor prognosis. We performed array comparative genomic hybridization analysis …
Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors
JA Veltman, J Fridlyand, S Pejavar, AB Olshen… - Cancer research, 2003 - AACR
Genome-wide copy number profiles were characterized in 41 primary bladder tumors using
array-based comparative genomic hybridization (array CGH). In addition to previously …
array-based comparative genomic hybridization (array CGH). In addition to previously …