Integrative genomic and gene-expression analyses have identified amplified oncogenes in
B-cell non-Hodgkin lymphoma (B-NHL), but the capability of such technologies to localize …

Microarray-based comparative genomic hybridization (array CGH) is a revolutionary
platform that was recently adopted in the clinical laboratory. This technology was first …

The integration of genomic and epigenomic data is an increasingly popular approach for
studying the complex mechanisms driving cancer development. We have developed a …

In this work, highly infiltrative brain tumors with a stem-like phenotype were established by
xenotransplantation of human brain tumors in immunodeficient nude rats. These tumors …

▪ Abstract Altering DNA copy number is one of the many ways that gene expression and
function may be modified. Some variations are found among normal individuals (,,), others …

Deletions of chromosome 8p are a recurrent event in B-cell non-Hodgkin lymphoma (B-
NHL), suggesting the presence of a tumor suppressor gene. We have characterized these …

A large database of copy number profiles from cancer genomes can facilitate the
identification of recurrent chromosomal alterations that often contain key cancer-related …

Genomic aberrations in a series of paired biopsy samples from patients who presented
initially with follicle center lymphoma (FCL) and subsequently transformed to diffuse large B …

Natural killer (NK)-cell malignancies are among the most aggressive lymphoid neoplasms
with very poor prognosis. We performed array comparative genomic hybridization analysis …

Genome-wide copy number profiles were characterized in 41 primary bladder tumors using
array-based comparative genomic hybridization (array CGH). In addition to previously …