Array CGH is a powerful technique for genomic studies of cancer. It enables one to carry out
genome-wide screening for regions of genetic alterations, such as chromosome gains and …

Microarray technology has undergone a rapid evolution. With widespread interest in large-
scale genomic research, an abundance of equipment and reagents have now become …

(57) ABSTRACT A neW method for genomic analysis, termed “Sequence Based
Karyotyping,” is described. Sequence-Based Karyo typing methods for the detection of …

Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to
radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are …

Removing noise from piecewise constant (PWC) signals is a challenging signal processing
problem arising in many practical contexts. For example, in exploration geosciences, noisy …

Structural changes (deletions, insertions, and inversions) between human and chimpanzee
genomes have likely had a significant impact on lineage-specific evolution because of their …

The combination of biology and nanotechnology has led to a new generation of
nanodevices that make it possible to characterize the chemical, mechanical, and other …

DNA Copy number variation (CNV) has recently gained considerable interest as a source of
genetic variation that likely influences phenotypic differences. Many statistical and …

The array CGH technique (Array Comparative Genome Hybridization) has been developed
to detect chromosomal copy number changes on a genome-wide and/or high-resolution …

Cancer progresses through a series of histopathological stages. Progression is thought to
be driven by the accumulation of genetic alterations and consequently gene expression …