[HTML][HTML] Neuroinflammation: friend and foe for ischemic stroke

RL Jayaraj, S Azimullah, R Beiram, FY Jalal… - Journal of …, 2019 - Springer
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

[PDF][PDF] The neurovascular unit coming of age: a journey through neurovascular coupling in health and disease

C Iadecola - Neuron, 2017 - cell.com
The concept of the neurovascular unit (NVU), formalized at the 2001 Stroke Progress
Review Group meeting of the National Institute of Neurological Disorders and Stroke …

Neuronal regulation of the blood–brain barrier and neurovascular coupling

L Kaplan, BW Chow, C Gu - Nature Reviews Neuroscience, 2020 - nature.com
To continuously process neural activity underlying sensation, movement and cognition, the
CNS requires a homeostatic microenvironment that is not only enriched in nutrients to meet …

Inflammation and depression: a causal or coincidental link to the pathophysiology?

BE Leonard - Acta neuropsychiatrica, 2018 - cambridge.org
This review summarises the evidence that chronic low grade inflammation triggers changes
that contribute to the mental and physical ill health of patients with major depression …

Spreading depression, spreading depolarizations, and the cerebral vasculature

C Ayata, M Lauritzen - Physiological reviews, 2015 - journals.physiology.org
Spreading depression (SD) is a transient wave of near-complete neuronal and glial
depolarization associated with massive transmembrane ionic and water shifts. It is …

Effects of anesthesia on cerebral blood flow, metabolism, and neuroprotection

AM Slupe, JR Kirsch - Journal of Cerebral Blood Flow & …, 2018 - journals.sagepub.com
Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

Glial and neuronal control of brain blood flow

D Attwell, AM Buchan, S Charpak, M Lauritzen… - Nature, 2010 - nature.com
Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these
cells control blood flow is crucial for understanding how neural computation is powered, for …

[HTML][HTML] The translational significance of the neurovascular unit

HL McConnell, CN Kersch, RL Woltjer… - Journal of biological …, 2017 - ASBMB
The mammalian brain is supplied with blood by specialized vasculature that is structurally
and functionally distinct from that of the periphery. A defining feature of this vasculature is a …

Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease

J Kur, EA Newman, T Chan-Ling - Progress in retinal and eye research, 2012 - Elsevier
We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …

[HTML][HTML] Intraventricular hemorrhage in premature infants: mechanism of disease

P Ballabh - Pediatric research, 2010 - nature.com
Intraventricular hemorrhage (IVH) is a major complication of prematurity. IVH typically
initiates in the germinal matrix, which is a richly vascularized collection of neuronal-glial …