Biological barriers are essential for the maintenance of homeostasis in health and disease.
Breakdown of the intestinal barrier is an essential aspect of the pathophysiology of …

Background Published small case series suggest that inflammatory bowel disease [IBD;
Crohn's disease (CD) or ulcerative colitis (UC)] and vasculitis co-occur more frequently than …

Chronic visceral pain syndromes are important clinical problems with largely unmet medical
needs. Based on the common overlap with other chronic disorders of visceral or somatic …

Inflammatory bowel diseases (IBD) are chronic inflammatory conditions affecting the
digestive system, comprising two main distinctive entities, ulcerative colitis (UC) and Crohn's …

Background Fatigue is the inability to achieve or maintain an expected work output resulting
from central or peripheral mechanisms. The prevalence of inflammatory bowel disease (IBD) …

Most gastrointestinal diseases and disorders (GIDD) are associated with depression,
anxiety, and cognitive dysfunction. This suggests that shared features of GIDD, particularly …

Background A growing number of neuroimaging studies suggest distinct neural changes in
inflammatory bowel diseases (IBDs). Whether such changes may show similar spatial …

Abstract Background: Whether Crohn's disease [CD] is correlated with brain structural
changes is unclear. This study examined changes in grey matter [GM] structures in CD …

Although the gut microbiota can influence central nervous system (CNS) autoimmune
diseases, the contribution of the intestinal epithelium to CNS autoimmunity is less clear …

Background and aims Inflammatory bowel disease (IBD), mainly categorized into Crohn's
disease (CD) and ulcerative colitis (UC), is a chronic relapsing gastrointestinal disorder that …