Not only dose oral administration have the highest safety, convenience and patient
compliance, but also can improve patients' quality of life and reduce health care costs in …

Nanopartículas poliméricas produzidas a partir de polímeros pré-formados, como os
poliésteres alifáticos, têm sido amplamente utilizadas para incorporar, principalmente …

The efficacy of paclitaxel (PTX) is limited due to its poor solubility, poor bioavailability, and
acquired drug resistance mechanisms. Designing paclitaxel prodrugs can improve its …

Oral chemotherapy is one of the most important issues in 21st century medicine. It may
radically change the current regimen of chemotherapy, as well as greatly improve the quality …

In the present study, a nanoparticulate system based on bio‐based waterborne
polyurethane for the controlled delivery of raloxifene‐hydrochloride, as a model and drug …

This article presents the potential of PLGA nanoparticles for the oral administration of drugs.
Different strategies are used to improve oral absorption of these nanoparticles. These …

Multidrug resistance (MDR) is one of the factors in the failure of anticancer chemotherapy. In
order to enhance the anticancer effect of P-glycoprotein (P-gp) substrates, inhibition of the P …

Multifunctional nanoparticles have been identified as a promising drug-delivery system for
sustainable drug release. The structural and size tunability and disease-targeting ability of …

Paclitaxel (PTX) is considered the blockbuster chemotherapy treatment for cancer.
Paclitaxel's (PTX) oral administration has proven to be extremely difficult, mostly because of …

The main objective of this study was to develop novel orally administrable tablets containing
solid dispersion granules (SDG) of amorphous paclitaxel (PTX) prepared by fluid bed …