Absorption mechanism of DHP107, an oral paclitaxel formulation that forms a hydrated lipidic sponge phase
Y Jang, HJ Chung, JW Hong, CW Yun… - Acta Pharmacologica …, 2017 - nature.com
Paclitaxel is a most widely used anticancer drug with low oral bioavailability, thus it is
currently administered via intravenous infusion. DHP107 is a lipid-based paclitaxel …
currently administered via intravenous infusion. DHP107 is a lipid-based paclitaxel …
Cytotoxic and antiangiogenic paclitaxel solubilized and permeation-enhanced by natural product nanoparticles
Z Liu, F Zhang, GY Koh, X Dong… - Anti-cancer …, 2015 - journals.lww.com
Paclitaxel (PTX) is one of the most potent intravenous chemotherapeutic agents to date, yet
an oral formulation has been problematic because of its low solubility and permeability …
an oral formulation has been problematic because of its low solubility and permeability …
Pharmaceutical technology for improving the bioavailability of natural products
S Paroha, RP Dewangan, PK Sahoo - … for Natural Products Delivery Vol. 1 …, 2020 - Springer
Therapeutic importance of natural products have been widely explored since ancient time
for benefit of human health although the clinical uses of these natural products still a …
for benefit of human health although the clinical uses of these natural products still a …
Paclitaxel-loaded colloidal silica and TPGS-based solid self-emulsifying system interferes Akt/MTOR pathway in MDA-MB-231 and demonstrates anti-tumor effect in …
A solid self-emulsifying drug delivery system (SEDDS) of paclitaxel (PTX) was developed
that could enhance its oral bioavailability and neutralize other niggles associated with …
that could enhance its oral bioavailability and neutralize other niggles associated with …
A focal adhesion kinase inhibitor 16-hydroxy-cleroda-3, 13-dien-16, 15-olide incorporated into enteric-coated nanoparticles for controlled anti-glioma drug delivery
V Thiyagarajan, SX Lin, CH Lee, CF Weng - Colloids and Surfaces B …, 2016 - Elsevier
Hydroxy-cleroda-3, 13-dien-16, 15-olide (HCD) which is extracted from a medicinal plant,
Polyalthia longifolia, was shown to exhibit anticancer activity through apoptosis and FAK …
Polyalthia longifolia, was shown to exhibit anticancer activity through apoptosis and FAK …
Liposomes as potential carrier system for targeted delivery of polyene antibiotics
SR Naik, SK Desai, PD Shah… - Recent patents on …, 2013 - ingentaconnect.com
The development of new therapeutic modalities involves the use of drug carrier, such as
liposomes, which can modify pharmacokinetic and bio-distribution of drug profile. Polyene …
liposomes, which can modify pharmacokinetic and bio-distribution of drug profile. Polyene …
PEGylated polyester-based nanoncologicals
C Conte, I d'Angelo, A Miro, F Ungaro… - Current topics in …, 2014 - ingentaconnect.com
Several PEGylated polyester-based nanoncologicals have been proposed in the literature,
some of them nowadays being under preclinical/clinical trials or marketed. In this review, we …
some of them nowadays being under preclinical/clinical trials or marketed. In this review, we …
[PDF][PDF] Development, characterization and evaluation of doxorubicin nanostructured lipid carriers for prostate cancer
HW Zhang, Q Dang, ZW Zhang, FS Wu - J buon, 2017 - jbuon.com
Purpose: The purpose of this study was to develop an optimised formulation for a
nanostructured lipid carrier (NLC) loaded with doxorubicin. Methods: A doxorubicin-loaded …
nanostructured lipid carrier (NLC) loaded with doxorubicin. Methods: A doxorubicin-loaded …
Formulations of water-soluble derivatives of vitamin E and compositions containing same
PJ Bromley - US Patent 9,351,517, 2016 - Google Patents
GJJVAFUKOBZPCB-ZGRPYONQSA-N (R)-3, 4-Dihydro-2-methyl-2-(4, 8, 12-trimethyl-3, 7,
11-tridecatrienyl)-2H-1-benzopyran-6-ol Chemical compound OC1= CC= C2OC (CC/C= C …
11-tridecatrienyl)-2H-1-benzopyran-6-ol Chemical compound OC1= CC= C2OC (CC/C= C …
[PDF][PDF] In situ cross linked chitosan-gellan gum polyelectrolyte complex based nanogels containing curcumin for delivery to cancer cells
HS Mahajan, PP Patil - Indian J. Pharm. Educ. Res, 2017 - ijper.org
Objective: The objective of this study is to prepare nanogels were prepared via ionic
complexation with negatively charged gellan gum. Method: Nanogel of curcumin was …
complexation with negatively charged gellan gum. Method: Nanogel of curcumin was …