The role of bile acids in carcinogenesis
Bile acids are soluble derivatives of cholesterol produced in the liver that subsequently
undergo bacterial transformation yielding a diverse array of metabolites. The bulk of bile …
undergo bacterial transformation yielding a diverse array of metabolites. The bulk of bile …
Cancer metastasis: molecular mechanisms and clinical perspectives
Metastatic progression combined with non-responsiveness towards systemic therapy often
shapes the course of disease for cancer patients and commonly determines its lethal …
shapes the course of disease for cancer patients and commonly determines its lethal …
Fap2 mediates Fusobacterium nucleatum colorectal adenocarcinoma enrichment by binding to tumor-expressed Gal-GalNAc
J Abed, JEM Emgård, G Zamir, M Faroja, G Almogy… - Cell host & …, 2016 - cell.com
Fusobacterium nucleatum is associated with colorectal cancer and promotes colonic tumor
formation in preclinical models. However, fusobacteria are core members of the human oral …
formation in preclinical models. However, fusobacteria are core members of the human oral …
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
Several studies have investigated links between the gut microbiome and colorectal cancer
(CRC), but questions remain about the replicability of biomarkers across cohorts and …
(CRC), but questions remain about the replicability of biomarkers across cohorts and …
The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next?
A Mitra, DA MacIntyre, JR Marchesi, YS Lee… - Microbiome, 2016 - Springer
The vaginal microbiota plays a significant role in health and disease of the female
reproductive tract. Next-generation sequencing techniques based upon the analysis of …
reproductive tract. Next-generation sequencing techniques based upon the analysis of …
The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
A Mitra, DA MacIntyre, G Ntritsos, A Smith… - Nature …, 2020 - nature.com
Emerging evidence suggests associations between the vaginal microbiota (VMB)
composition, human papillomavirus (HPV) infection, and cervical intraepithelial neoplasia …
composition, human papillomavirus (HPV) infection, and cervical intraepithelial neoplasia …
Does the vaginal microbiota play a role in the development of cervical cancer?
M Kyrgiou, A Mitra, AB Moscicki - Translational Research, 2017 - Elsevier
Persistent infection with oncogenic human papillomavirus (HPV) is necessary but not
sufficient for the development of cervical cancer. The factors promoting persistence as well …
sufficient for the development of cervical cancer. The factors promoting persistence as well …
Microbial carcinogenesis: Lactic acid bacteria in gastric cancer
K Vinasco, HM Mitchell, NO Kaakoush… - … et Biophysica Acta (BBA …, 2019 - Elsevier
While Helicobacter pylori is a fundamental risk factor, gastric cancer (GC) aetiology involves
combined effects of microbial (both H. pylori and non-H. pylori), host and environmental …
combined effects of microbial (both H. pylori and non-H. pylori), host and environmental …
The impact of the human microbiome in tumorigenesis, cancer progression, and biotherapeutic development
CM Doocey, K Finn, C Murphy, CM Guinane - BMC microbiology, 2022 - Springer
Background Cancer impacts millions of lives globally each year, with approximately 10
million cancer-related deaths recorded worldwide in 2020. Mounting research has …
million cancer-related deaths recorded worldwide in 2020. Mounting research has …
Food additives, contaminants and other minor components: Effects on human gut microbiota—A review
P Roca-Saavedra, V Mendez-Vilabrille… - Journal of physiology …, 2018 - Springer
Gut bacteria play an important role in several metabolic processes and human diseases,
such as obesity and accompanying co-morbidities, such as fatty liver disease, insulin …
such as obesity and accompanying co-morbidities, such as fatty liver disease, insulin …