Accuracy of line probe assays for the diagnosis of pulmonary and multidrug-resistant tuberculosis: a systematic review and meta-analysis
RR Nathavitharana, PGT Cudahy… - European …, 2017 - Eur Respiratory Soc
Only 25% of multidrug-resistant tuberculosis (MDR-TB) cases are currently diagnosed. Line
probe assays (LPAs) enable rapid drug-susceptibility testing for rifampicin (RIF) and …
probe assays (LPAs) enable rapid drug-susceptibility testing for rifampicin (RIF) and …
Drug resistance mechanisms and drug susceptibility testing for tuberculosis
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) is the deadliest infectious
disease and the associated global threat has worsened with the emergence of drug …
disease and the associated global threat has worsened with the emergence of drug …
Diagnostics for pulmonary tuberculosis
Tuberculosis (TB) remains a leading cause of human suffering and mortality despite
decades of effective treatment being available. Accurate and timely diagnosis remains an …
decades of effective treatment being available. Accurate and timely diagnosis remains an …
Systematic review, meta-analysis and economic modelling of molecular diagnostic tests for antibiotic resistance in tuberculosis.
F Drobniewski, M Cooke, J Jordan… - Health technology …, 2015 - researchonline.lshtm.ac.uk
BACKGROUND: Drug-resistant tuberculosis (TB), especially multidrug-resistant (MDR,
resistance to rifampicin and isoniazid) disease, is associated with a worse patient outcome …
resistance to rifampicin and isoniazid) disease, is associated with a worse patient outcome …
[HTML][HTML] Prevalence, risk factors, and treatment outcomes of isoniazid-and rifampicin-mono-resistant pulmonary tuberculosis in Lima, Peru
L Villegas, L Otero, TR Sterling, MA Huaman… - PloS one, 2016 - journals.plos.org
Background Isoniazid and rifampicin are the two most efficacious first-line agents for
tuberculosis (TB) treatment. We assessed the prevalence of isoniazid and rifampicin mono …
tuberculosis (TB) treatment. We assessed the prevalence of isoniazid and rifampicin mono …
[HTML][HTML] GenoType MTBDRplus Assay for Rapid Detection of Multidrug Resistance in Mycobacterium tuberculosis: A Meta-Analysis
Y Bai, Y Wang, C Shao, Y Hao, Y Jin - PloS one, 2016 - journals.plos.org
Background There is an urgent demand for rapid and accurate drug-susceptibility testing for
the detection of multidrug-resistant tuberculosis. The GenoType MTBDR plus assay is a …
the detection of multidrug-resistant tuberculosis. The GenoType MTBDR plus assay is a …
[HTML][HTML] Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance
We compared the ability of commercial and non-commercial, phenotypic and genotypic
rapid drug susceptibility tests (DSTs) to detect rifampicin resistance (RR)-conferring …
rapid drug susceptibility tests (DSTs) to detect rifampicin resistance (RR)-conferring …
[HTML][HTML] The diagnostic accuracy of the MTBDRplus and MTBDRsl assays for drug-resistant TB detection when performed on sputum and culture isolates
M Tomasicchio, G Theron, E Pietersen, E Streicher… - Scientific reports, 2016 - nature.com
Although molecular tests for drug-resistant TB perform well on culture isolates, their
accuracy using clinical samples, particularly from TB and HIV-endemic settings, requires …
accuracy using clinical samples, particularly from TB and HIV-endemic settings, requires …
[HTML][HTML] Effect of a comprehensive programme to provide universal access to care for sputum-smear-positive multidrug-resistant tuberculosis in China: a before-and …
Background China has a quarter of all patients with multidrug-resistant tuberculosis
(MDRTB) worldwide, but less than 5% are in quality treatment programmes. In a before-and …
(MDRTB) worldwide, but less than 5% are in quality treatment programmes. In a before-and …
Evolution of phenotypic and molecular drug susceptibility testing
DM Cirillo, P Miotto, E Tortoli - … tuberculosis complex: its role in biology …, 2017 - Springer
Abstract Drug Resistant Tuberculosis (DRTB) is an emerging problem world-wide. In order
to control the disease and decrease the number of cases overtime a prompt diagnosis …
to control the disease and decrease the number of cases overtime a prompt diagnosis …