Disruption of biofilm by bacteriophages in clinically relevant settings

CJ Kovacs, EM Rapp, SM McKenzie, MZ Mazur… - Military …, 2024 - academic.oup.com
Introduction Antibiotic-resistant bacteria are a growing threat to civilian and military health
today. Although infections were once easily treatable by antibiotics and wound cleaning, the …

The role of neutrophils in diabetic ulcers and targeting therapeutic strategies

XX Ma, QK Liu, L Kuai, X Ma, Y Luo, Y Luo… - International …, 2023 - Elsevier
Diabetic ulcers (DUs) are a common complication of diabetes with high morbidity, poor
prognosis, and a high socio-economic burden. The main pathological manifestations of DUs …

Self-powered biodegradable and antibacterial MoS2-based triboelectric nanogenerators for the acceleration of wound healing in diabetes

H Yu, J Kong, M Mao, X Ge, Y Sun, J Liu, J Ye, Y Wang - Nano Energy, 2024 - Elsevier
Recently, there has been significant interests in the use of wearable triboelectric
nanogenerators (TENGs) to accelerate wound healing. In this study, a single-electrode …

Therapeutic phages as modulators of the immune response: practical implications

A Górski, R Międzybrodzki… - Clinical Infectious …, 2023 - academic.oup.com
While the medical community awaits formal proof of the efficacy of phage therapy, as is
required by evidence-based medicine, existing data suggest that phages could also be …

[HTML][HTML] Bacteriophages as nanocarriers for targeted drug delivery and enhanced therapeutic effects

SC Emencheta, AL Onugwu, CF Kalu, PN Ezinkwo… - Materials …, 2024 - pubs.rsc.org
The effective delivery of therapeutic agents is as important as the active therapeutic agent
because it may make or mar the outcome. Traditional/conventional drug delivery systems …

[HTML][HTML] Annexin A12–26 hydrogel improves healing properties in an experimental skin lesion after induction of type 1 diabetes

M Sant, CF Amantino, RA Silva, CD Gil… - Biomedicine & …, 2023 - Elsevier
Diabetes mellitus (DM) is characterized by metabolic alterations that involve defects in the
secretion and/or action of insulin, being responsible for several complications, such as …

[HTML][HTML] 五株克雷伯氏菌噬菌体的生物学特性及比较基因组学研究

王猛, 王雪, 赵佳男, 曾君, 左君豪, 郭志良… - 微生物 …, 2023 - actamicro.ijournals.cn
[目的] 耐药性克雷伯氏菌属(Klebsiella) 的细菌作为人类感染的重要病原,
是临床治疗重要的挑战. 本研究对多株克雷伯氏菌裂解性噬菌体的生物学特性和基因组特征进行 …

Understanding and treating diabetic foot ulcers: Insights into the role of cutaneous microbiota and innovative therapies

P Norton, P Trus, F Wang, MJ Thornton… - Skin Health and …, 2024 - Wiley Online Library
Background Notoriously known as the silent pandemic, chronic, non‐healing diabetic foot
ulcers (DFUs), pose a significant rate of incidence for amputation and are a major cause of …

Infection in Diabetes: Epidemiology, Immune Dysfunctions, and Therapeutics

R Roy, R Singh, SH Shafikhani - The Diabetic Foot: Medical and Surgical …, 2024 - Springer
Diabetes is a chronic metabolic disorder that affects approximately 10% of the global
population. Unfortunately, diabetic individuals are also at a high risk of developing diabetic …

Bacteriophage therapy in diabetic foot ulcer caused by Pseudomonas aeruginosa.

AC Sasi, TC Sanjeevi, RC Sambandam… - Microbes and …, 2024 - mid.journals.ekb.eg
Background: Bacteriophages are viruses that are used to destroy bacteria without harming
host cells. As a result, it is thought that they can be used to treat bacterial infections alone or …