Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …

Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …

Background The management of minimal, mild and moderate head injuries is still
controversial. In 2000, the Scandinavian Neurotrauma Committee (SNC) presented …

The acknowledgement of risks for traumatic brain injury in American football players has
prompted studies for sideline concussion diagnosis and testing for neurological deficits …

Accurate diagnosis of traumatic brain injury (TBI) is critical to effective management and
intervention, but can be challenging in patients with mild TBI. A substantial number of …

Mild traumatic brain injury (mTBI) is a common occurrence, with over 3 million cases
reported every year in the United States. While research into the underlying pathophysiology …

Head computed tomography (CT) imaging is still a commonly obtained diagnostic test for
patients with minor head injury despite availability of clinical decision rules to guide imaging …

TBI (traumatic brain injury) is a major cause of death among youth in industrialized societies.
Brain damage following traumatic injury is a result of direct and indirect mechanisms; …

Importance A proportion of patients experience long-lasting symptoms following mild
traumatic brain injury (MTBI). The postconcussion syndrome (PCS), included in theDSM-IV …

Background Mild traumatic brain injury (TBI) is associated with substantial costs due to over-
triage of patients to computed tomography (CT) scanning, despite validated decision rules …