Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by protein
aggregation in the brain. Recent studies have revealed the critical role of microglia in AD …

Ischemia-reperfusion injury is a major cause of acute kidney injury. Recent studies on the
pathophysiology of ischemia-reperfusion-induced acute kidney injury showed that …

Macrophages are professional antigen-presenting cells and serve as the first line of defense
against invading pathogens. Macrophages are polarized toward the proinflammatory …

Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …

Background Neuroinflammation has been reported as a potential contributing factor to brain
diseases, and is characterized by activated microglia with release of multiple inflammatory …

Inflammation is a severe topic in the immune system and play a role as pro-inflammatory
mediators. In response to such inflammatory substances, immune cells release cytokines …

Inflammatory bowel disease (IBD) is an idiopathic, chronic condition characterized by
episodes of inflammation in the gastrointestinal tract. The nuclear factor κB (NF-κB) system …

Cell cycle and apoptosis regulator 2 (CCAR2), also known as deleted in breast cancer 1
(DBC1), has been recently identified as a master regulator of transcriptional processes and …

The involvement of central and peripheral inflammation in the pathogenesis and prognosis
of major depressive disorder (MDD) has been demonstrated. The increase of pro …