A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options

A Garakani, JW Murrough, RC Freire, RP Thom… - Frontiers in …, 2020 - frontiersin.org
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

[HTML][HTML] The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

[HTML][HTML] Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders

MS García-Gutiérrez, F Navarrete, A Gasparyan… - Biomolecules, 2020 - mdpi.com
The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

Diversity of molecular targets and signaling pathways for CBD

DL de Almeida, LA Devi - Pharmacology research & …, 2020 - Wiley Online Library
Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …

[HTML][HTML] Industrial Hemp (Cannabis sativa subsp. sativa) as an Emerging Source for Value-Added Functional Food Ingredients and Nutraceuticals

HPV Rupasinghe, A Davis, SK Kumar, B Murray… - Molecules, 2020 - mdpi.com
Industrial hemp (Cannabis sativa L., Cannabaceae) is an ancient cultivated plant originating
from Central Asia and historically has been a multi-use crop valued for its fiber, food, and …

Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies

DP Finn, S Haroutounian, AG Hohmann, E Krane… - Pain, 2021 - journals.lww.com
This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

[HTML][HTML] Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

D De Gregorio, RJ McLaughlin, L Posa… - Pain, 2019 - journals.lww.com
Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …

[HTML][HTML] Medicinal cannabis for psychiatric disorders: a clinically-focused systematic review

J Sarris, J Sinclair, D Karamacoska, M Davidson, J Firth - BMC psychiatry, 2020 - Springer
Background Medicinal cannabis has received increased research attention over recent
years due to loosening global regulatory changes. Medicinal cannabis has been reported to …