Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation

HN Murthy, EJ Lee, KY Paek - Plant Cell, Tissue and Organ Culture …, 2014 - Springer
Plant cell and organ cultures have emerged as potential sources of secondary metabolites,
which are used as pharmaceuticals, agrochemicals, flavors, fragrances, coloring agents …

Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield

T Isah, S Umar, A Mujib, MP Sharma… - Plant Cell, Tissue and …, 2018 - Springer
Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …

Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor

MA Baque, SH Moh, EJ Lee, JJ Zhong, KY Paek - Biotechnology Advances, 2012 - Elsevier
The increasing global demand for biomass of medicinal plant resources reflects the issues
and crisis created by diminishing renewable resources and increasing consumer …

Engineering secondary metabolite production in hairy roots

S Chandra, R Chandra - Phytochemistry reviews, 2011 - Springer
Plants are a rich source of valuable secondary metabolites. Plant cell culture technologies
developed in the past as possible tools for secondary metabolites production. In most cases …

Sucrose-induced osmotic stress affects biomass, metabolite, and antioxidant levels in root suspension cultures of Hypericum perforatum L.

XH Cui, HN Murthy, CH Wu, KY Paek - Plant Cell, Tissue and Organ …, 2010 - Springer
In this study, we investigated the influence of initial sucrose concentration on the
accumulation of biomass, phenols, flavonoids, chlorogenic acid, and hypericin in …

Adventitious root culture—an alternative strategy for secondary metabolite production: a review

MN Khanam, M Anis, SB Javed, J Mottaghipisheh… - Agronomy, 2022 - mdpi.com
Medicinal plants are valuable sources of botanical drugs, extracts and pure compounds.
Although several species can be propagated or collected, the access to herbal material is …

[HTML][HTML] Adventitious root culture for secondary metabolite production in medicinal plants: a review

E Rahmat, Y Kang - Journal of Plant Biotechnology, 2019 - kspbtjpb.org
Medicinal plants are high-value natural resources that have been used as precautionary
drugs by many people globally. The increasing global demand for bioactive compounds …

Effects of some elicitors on tanshinone production in adventitious root cultures of Perovskia abrotanoides Karel

A Zaker, C Sykora, F Gössnitzer, P Abrishamchi… - Industrial Crops and …, 2015 - Elsevier
In this study, we investigated the effects of different biotic and abiotic elicitors including yeast
extract (YE), methyl jasmonate (MJ), AgNO 3 and sorbitol on biomass and production of …

In vitro strategies for the enhancement of secondary metabolite production in plants: a review

MA Fazili, I Bashir, M Ahmad, U Yaqoob… - Bulletin of the National …, 2022 - Springer
Background Plants are the prime source of vital secondary metabolites (SMs) which are
medicinally important for drug development, and these secondary metabolites are often …

Tools for biotechnological production of useful phytochemicals from adventitious root cultures

HN Murthy, VS Dandin, KY Paek - Phytochemistry reviews, 2016 - Springer
Adventitious roots are natural roots which develop from the differentiated cells of any organ
such as leaf, root or stem. These roots are attractive source of phytochemicals due to their …