Periodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is
increasing all over the world. In patients with periodontitis, there is gradual destruction of the …

Gingival tissues are attacked by oral pathogens which can induce inflammatory reactions.
The immune-inflammatory responses play essential roles in the patient susceptibility to …

Mitochondria are essential organelles in balancing oxidative stress and cell death during
cancer cell proliferation. Rapid tumor growth induces tremendous stress on mitochondria …

Tumor necrosis factor-α-induced protein 8 (TNFAIP8) expression has been linked to tumor
progression in various cancer types, but the detailed mechanisms of TNFAIP8 are not fully …

Tumor necrosis factor (TNF) is the first cytokine used in tumor biotherapy, but TNF-related
drugs are limited by the lack of specific targets. Tumor necrosis factor alpha-induced …

Kidney fibrosis, characterized by the activation and expansion of the matrix-producing
fibroblasts, is the common outcome of chronic kidney disease (CKD). While fibroblast …

Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8/TIPE) family proteins are
known to be involved in maintaining immune homeostasis. The TIPE family contains four …

Lung cancer is the foremost cause of cancer related mortality among men and one of the
most fatal cancers among women. Notably, the 5-year survival rate of lung cancer is very …

Coronary artery disease (CAD) is a common cardiovascular disease, mainly due to vascular
endothelial cell (VEC) injury caused by atherosclerosis. Circular RNA has been shown to be …

Background and aim Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive
breast cancer with highly variable clinical behavior, but risk stratification is still challenging …