Periodontitis and its inflammatory changes linked to various systemic diseases: a review of its underlying mechanisms
Periodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is
increasing all over the world. In patients with periodontitis, there is gradual destruction of the …
increasing all over the world. In patients with periodontitis, there is gradual destruction of the …
[HTML][HTML] Periodontitis and oral cancer-current concepts of the etiopathogenesis
Gingival tissues are attacked by oral pathogens which can induce inflammatory reactions.
The immune-inflammatory responses play essential roles in the patient susceptibility to …
The immune-inflammatory responses play essential roles in the patient susceptibility to …
TIPE3 represses head and neck squamous cell carcinoma progression via triggering PGAM5 mediated mitochondria dysfunction
W Chen, X Chen, L Wang, R Yang, W Zhang… - Cell Death & …, 2023 - nature.com
Mitochondria are essential organelles in balancing oxidative stress and cell death during
cancer cell proliferation. Rapid tumor growth induces tremendous stress on mitochondria …
cancer cell proliferation. Rapid tumor growth induces tremendous stress on mitochondria …
TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation
Tumor necrosis factor-α-induced protein 8 (TNFAIP8) expression has been linked to tumor
progression in various cancer types, but the detailed mechanisms of TNFAIP8 are not fully …
progression in various cancer types, but the detailed mechanisms of TNFAIP8 are not fully …
Tumor necrosis factor alpha-induced proteins in malignant tumors: progress and prospects
F Guo, Y Yuan - OncoTargets and therapy, 2020 - Taylor & Francis
Tumor necrosis factor (TNF) is the first cytokine used in tumor biotherapy, but TNF-related
drugs are limited by the lack of specific targets. Tumor necrosis factor alpha-induced …
drugs are limited by the lack of specific targets. Tumor necrosis factor alpha-induced …
Kidney tubular epithelial cells control interstitial fibroblast fate by releasing TNFAIP8-encapsulated exosomes
X Liu, Z Liu, C Wang, J Miao, S Zhou, Q Ren… - Cell Death & …, 2023 - nature.com
Kidney fibrosis, characterized by the activation and expansion of the matrix-producing
fibroblasts, is the common outcome of chronic kidney disease (CKD). While fibroblast …
fibroblasts, is the common outcome of chronic kidney disease (CKD). While fibroblast …
[HTML][HTML] TNFAIP8: inflammation, immunity and human diseases
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8/TIPE) family proteins are
known to be involved in maintaining immune homeostasis. The TIPE family contains four …
known to be involved in maintaining immune homeostasis. The TIPE family contains four …
Loss of TIPE3 reduced the proliferation, survival and migration of lung cancer cells through inactivation of Akt/mTOR, NF-κB, and STAT-3 signaling cascades
Lung cancer is the foremost cause of cancer related mortality among men and one of the
most fatal cancers among women. Notably, the 5-year survival rate of lung cancer is very …
most fatal cancers among women. Notably, the 5-year survival rate of lung cancer is very …
Knockdown of circ_0004104 alleviates oxidized low-density lipoprotein-induced vascular endothelial cell injury by regulating miR-100/TNFAIP8 Axis
P Ji, X Song, Z Lv - Journal of Cardiovascular Pharmacology, 2021 - journals.lww.com
Coronary artery disease (CAD) is a common cardiovascular disease, mainly due to vascular
endothelial cell (VEC) injury caused by atherosclerosis. Circular RNA has been shown to be …
endothelial cell (VEC) injury caused by atherosclerosis. Circular RNA has been shown to be …
[HTML][HTML] Expression of immune-related genes and breast cancer recurrence in women with ductal carcinoma in situ
E Guerini-Rocco, F Bellerba, A Concardi… - European Journal of …, 2024 - Elsevier
Background and aim Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive
breast cancer with highly variable clinical behavior, but risk stratification is still challenging …
breast cancer with highly variable clinical behavior, but risk stratification is still challenging …