Highlights in heart failure

D Tomasoni, M Adamo, CM Lombardi… - ESC heart …, 2019 - Wiley Online Library
Heart failure (HF) remains a major cause of mortality, morbidity, and poor quality of life. It is
an area of active research. This article is aimed to give an update on recent advances in all …

Heart failure in the last year: progress and perspective

D Tomasoni, M Adamo, MS Anker… - ESC Heart …, 2020 - Wiley Online Library
Research about heart failure (HF) has made major progress in the last years. We give here
an update on the most recent findings. Landmark trials have established new treatments for …

[HTML][HTML] Adverse cardiac remodelling after acute myocardial infarction: old and new biomarkers

AE Berezin, AA Berezin - Disease Markers, 2020 - hindawi.com
The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial
infarction (AMI) does not decrease regardless of implementation of new technologies …

Biomarkers in heart failure: the past, current and future

M Sarhene, Y Wang, J Wei, Y Huang, M Li, L Li… - Heart failure …, 2019 - Springer
Despite the enhanced knowledge of the pathophysiology of heart failure (HF), it still remains
a serious syndrome with substantial morbidity, mortality, and frequent hospitalizations …

[HTML][HTML] Biomarkers for heart failure prognosis: proteins, genetic scores and non-coding RNAs

A Shrivastava, T Haase, T Zeller… - Frontiers in cardiovascular …, 2020 - frontiersin.org
Heart failure (HF) is a complex disease in which cardiomyocyte injury leads to a cascade of
inflammatory and fibrosis pathway activation, thereby causing decrease in cardiac function …

High-sensitivity C-reactive protein in chronic heart failure: patient characteristics, phenotypes, and mode of death

P Pellicori, J Zhang, J Cuthbert, A Urbinati… - Cardiovascular …, 2020 - academic.oup.com
Aims Plasma concentrations of high-sensitivity C-reactive protein (hsCRP) are often raised
in chronic heart failure (CHF) and might indicate inflammatory processes that could be a …

[HTML][HTML] Translational studies of adrenomedullin and related peptides regarding cardiovascular diseases

T Kita, K Kitamura - Hypertension Research, 2022 - nature.com
Adrenomedullin (AM) is a vasodilative peptide with various physiological functions,
including the maintenance of vascular tone and endothelial barrier function. AM levels are …

Clinical potential of adrenomedullin signaling in the cardiovascular system

L Bálint, NP Nelson-Maney, Y Tian, SD Serafin… - Circulation …, 2023 - Am Heart Assoc
Numerous clinical studies have revealed the utility of circulating AM (adrenomedullin) or MR-
proAM (mid-regional proAM 45-92) as an effective prognostic and diagnostic biomarker for a …

Persistent congestion, renal dysfunction and inflammatory cytokines in acute heart failure: a prognosis study

NR Pugliese, I Fabiani, L Conte, L Nesti… - Journal of …, 2020 - journals.lww.com
Aims Chronic kidney dysfunction (CKD) and persistent congestion influence heart failure
prognosis, but little is known about the role of inflammation in this association. We assessed …

A test in context: interpretation of high-sensitivity cardiac troponin assays in different clinical settings

I Raber, CP McCarthy, JL Januzzi Jr - Journal of the American College of …, 2021 - jacc.org
High-sensitivity cardiac troponin (hs-cTn) assays have the ability to detect minute troponin
concentrations and resolve minor changes in biomarker concentrations. Clinically, this …