Prostate cancer and inflammation: the evidence

KS Sfanos, AM De Marzo - Histopathology, 2012 - Wiley Online Library
Sfanos KS & De Marzo AM (2012) Histopathology 60, 199–215 Prostate cancer and
inflammation: the evidence Chronic inflammation is now known to contribute to several …

[HTML][HTML] Tomatoes, lycopene, and prostate cancer: what have we learned from experimental models?

NE Moran, JM Thomas-Ahner, L Wan, KE Zuniga… - The Journal of …, 2022 - Elsevier
Human epidemiology suggests a protective effect of tomatoes or tomato phytochemicals,
such as lycopene, on prostate cancer risk. However, human epidemiology alone cannot …

The role of oxidative stress in prostate cancer

G Gupta-Elera, AR Garrett, RA Robison… - European Journal of …, 2012 - journals.lww.com
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are not only
byproducts of normal cellular metabolism, but also play important roles in cell signaling …

Plant science and human nutrition: challenges in assessing health-promoting properties of phytochemicals

MH Traka, RF Mithen - The Plant Cell, 2011 - academic.oup.com
The rise in noncommunicable chronic diseases associated with changing diet and lifestyles
throughout the world is a major challenge for society. It is possible that certain dietary …

Dietary tomato and lycopene impact androgen signaling-and carcinogenesis-related gene expression during early TRAMP prostate carcinogenesis

L Wan, HL Tan, JM Thomas-Ahner, DK Pearl… - Cancer Prevention …, 2014 - AACR
Consumption of tomato products containing the carotenoid lycopene is associated with a
reduced risk of prostate cancer. To identify gene expression patterns associated with early …

Identification and quantification of anthocyanins in transgenic purple tomato

X Su, J Xu, D Rhodes, Y Shen, W Song, B Katz… - Food Chemistry, 2016 - Elsevier
Anthocyanins are natural pigments derived from the phenylpropanoid pathway. Most
tomatoes produce little anthocyanins, but the transgenic purple tomato biosynthesizes a …

New vinegar produced by tomato suppresses adipocyte differentiation and fat accumulation in 3T3-L1 cells and obese rat model

JH Lee, HD Cho, JH Jeong, MK Lee, YK Jeong… - Food chemistry, 2013 - Elsevier
There is an increasing surplus of tomatoes that are abandoned due to their failure to meet
customer standards. Therefore, to allow both value additions and the effective reuse of …

β-Carotene 9′, 10′ oxygenase modulates the anticancer activity of dietary tomato or lycopene on prostate carcinogenesis in the TRAMP model

HL Tan, JM Thomas-Ahner, NE Moran… - Cancer Prevention …, 2017 - AACR
The hypothesis that dietary tomato consumption or the intake of the carotenoid lycopene
inhibits prostate cancer arose from epidemiologic studies and is supported by preclinical …

[HTML][HTML] Improving whole tomato transformation for prostate health: benign prostate hypertrophy as an exploratory model

PG Natali, M Piantelli, M Minacori, M Eufemi… - International Journal of …, 2023 - mdpi.com
It is well-established that the beneficial properties of single phytonutrients can be better
attained when they are taken with the complex of the molecules present in their natural …

[HTML][HTML] Xanthohumol impairs human prostate cancer cell growth and invasion and diminishes the incidence and progression of advanced tumors in TRAMP mice

R Venè, R Benelli, S Minghelli, S Astigiano, F Tosetti… - Molecular …, 2012 - Springer
Despite recent advances in understanding the biological basis of prostate cancer,
management of the disease, especially in the phase resistant to androgen ablation, remains …