Parkinson's disease is a progressive neurodegenerative disorder. The classical motor
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …

Neuroplasticity can be defined as the ability of the nervous system to respond to intrinsic or
extrinsic stimuli by reorganizing its structure, function and connections. Major advances in …

Recent studies indicate that dopamine neurons in the ventral tegmental area (VTA) and
substantia nigra pars compacta (SNc) convey distinct signals. To explore this difference, we …

Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …

Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory
hypokinetic and hyperkinetic movement disorders, and it is being explored for a variety of …

Temporal interference (TI) is a non-invasive neurostimulation technique that utilizes high-
frequency external electric fields to stimulate deep neuronal structures without affecting …

For over a century, electrical microstimulation has been the most direct method for causally
linking brain function with behavior. Despite this long history, it is still unclear how the activity …

Deep brain stimulation (DBS) is an established medical therapy for the treatment of
movement disorders and shows great promise for several other neurological disorders …

The cerebellum is best known for its role in controlling motor behaviors. However, recent
work supports the view that it also influences non-motor behaviors. The contribution of the …

Deep brain stimulation (DBS) has revolutionized the clinical care of late‐stage Parkinson's
disease and shows promise for improving the treatment of intractable neuropsychiatric …