The 2019 Nîmes International Symposium in Antibiotic Therapy Optimisation aimed at
determining the best approaches of a number of the antibiotic management strategies for …

This review sets out to evaluate the current evidence on the impact of inappropriate therapy
on bloodstream infections (BSI) and associated mortality. Based on the premise that better …

Background In a previous study, we demonstrated that rapid antibiotic susceptibility tests
(ASTs) can be performed directly on blood culture samples tested on Mueller–Hinton Rapid …

Background Severe sepsis is a potentially deadly illness and always requires intensive care.
Do-not-resuscitate (DNR) orders remain a debated issue in critical care and limited data …

Sepsis is a severe and frequently occurring clinical syndrome, caused by the inflammatory
response to infections. Recent studies on the human transcriptome during sepsis have …

Studies indicate that sepsis and septic shock in resourcelimited settings are at least as
common as in resourcerich settings. The surviving sepsis campaign (SSC) guidelines have …

OBJECTIVES: Although the Surviving Sepsis Campaign bundle recommends obtaining
blood cultures within 1 hour of sepsis recognition, adherence is suboptimal in many settings …

Purpose New techniques are needed to speed-up the identification and antimicrobial
susceptibility testing (AST) of bacteria associated with bloodstream infections. Alfred 60/AST …

Background: Significant interactions between drugs, extracorporeal membrane oxygenation
(ECMO) circuits and critical illness may affect the pharmacokinetic properties of antibiotics in …

Purpose This report describes a comprehensive pharmacy-driven rapid bacteremia
response program. Summary This novel program positioned the pharmacy department at a …