Intelligent poly (l-histidine)-based nanovehicles for controlled drug delivery

Y Zhang, I Kim, Y Lu, Y Xu, DG Yu, W Song - Journal of Controlled Release, 2022 - Elsevier
Stimuli-responsive drug delivery systems based on polymeric nanovehicles are among the
most promising treatment regimens for malignant cancers. Such intelligent systems that …

Lanthanide porphyrinoids as molecular theranostics

GQ Jin, CV Chau, JF Arambula, S Gao… - Chemical Society …, 2022 - pubs.rsc.org
In recent years, lanthanide (Ln) porphyrinoids have received increasing attention as
theranostics. Broadly speaking, the term 'theranostics' refers to agents designed to allow …

Photodecaging of a mitochondria-localized iridium (III) endoperoxide complex for two-photon photoactivated therapy under hypoxia

S Kuang, F Wei, J Karges, L Ke, K Xiong… - Journal of the …, 2022 - ACS Publications
Despite the clinical success of photodynamic therapy (PDT), the application of this medical
technique is intrinsically limited by the low oxygen concentrations found in cancer tumors …

Photo‐Reduction with NIR Light of Nucleus‐Targeting PtIV Nanoparticles for Combined Tumor‐Targeted Chemotherapy and Photodynamic Immunotherapy

D Wei, Y Huang, B Wang, L Ma… - Angewandte Chemie …, 2022 - Wiley Online Library
The development of PtIV prodrugs which are selectively reduced within cancerous cells into
their PtII therapeutically active species has received increasing attention within the last …

A Biodegradable Iridium (III) Coordination Polymer for Enhanced Two‐Photon Photodynamic Therapy Using an Apoptosis–Ferroptosis Hybrid Pathway

L Ke, F Wei, L Xie, J Karges, Y Chen, L Ji… - Angewandte …, 2022 - Wiley Online Library
The clinical application of photodynamic therapy is hindered by the high glutathione
concentration, poor cancer‐targeting properties, poor drug loading into delivery systems …

Click Synthesis Enabled Sulfur Atom Strategy for Polymerization‐Enhanced and Two‐Photon Photosensitization

C Li, J Liu, Y Hong, R Lin, Z Liu, M Chen… - Angewandte Chemie …, 2022 - Wiley Online Library
Facile tailoring of photosensitizers (PSs) with advanced and synergetic properties is highly
expected to broaden and deepen photodynamic therapy (PDT) applications. Herein, a …

Near-infrared light-excited reactive oxygen species generation by thulium oxide nanoparticles

D Duosiken, R Yang, Y Dai, Z Marfavi… - Journal of the …, 2022 - ACS Publications
Exploring materials that can absorb near-infrared (NIR) light to produce reactive oxygen
species (ROS) is necessary for many fields. Herein we show that thulium oxide …

Lanthanide nanoparticles for near-infrared II theranostics

T Jia, G Chen - Coordination Chemistry Reviews, 2022 - Elsevier
Fluorescence imaging in the second near-infrared biological window (NIR-II, 1000–1700
nm) presents unparalleled merits of non-invasion, high sensitivity, deeper penetration depth …

Photosensitizer encryption with aggregation enhanced singlet oxygen production

C Bloyet, F Sciortino, Y Matsushita… - Journal of the …, 2022 - ACS Publications
Chromophores that generate singlet oxygen (1O2) in water are essential to developing
noninvasive disease treatments using photodynamic therapy (PDT). A facile approach for …

[HTML][HTML] Ru (II)-modified TiO2 nanoparticles for hypoxia-adaptive photo-immunotherapy of oral squamous cell carcinoma

JY Zhou, WJ Wang, CY Zhang, YY Ling, XJ Hong, Q Su… - Biomaterials, 2022 - Elsevier
The alternations in the hypoxic and immune microenvironment are closely related to the
therapeutic effect and prognosis of oral squamous cell carcinoma (OSCC). Herein, a new …