NF-κB pathway consists of canonical and non-canonical pathways. The canonical NF-κB is
activated by various stimuli, transducing a quick but transient transcriptional activity, to …

The tumor necrosis factor (TNF) and TNF receptor (TNFR) superfamilies (TNFSF/TNFRSF)
include 19 ligands and 29 receptors that play important roles in the modulation of cellular …

Lymph nodes (LNs) are strategically positioned at dedicated sites throughout the body to
facilitate rapid and efficient immunity. Central to the structural integrity and framework of LNs …

Although activity that induced tumor regression was observed and termed tumor necrosis
factor (TNF) as early as the 1960s, the true identity of TNF was not clear until 1984, when …

The noncanonical nuclear factor‐κB (NF‐κB) signaling pathway mediates activation of the
p52/RelB NF‐κB complex and, thereby, regulates specific immunological processes. This …

The TNF and TNF Receptor Superfamilies: Cell Skip to Main Content Advertisement Cell This
journal offers authors two options (open access or subscription) to publish research This …

The spleen combines the innate and adaptive immune system in a uniquely organized way.
The structure of the spleen enables it to remove older erythrocytes from the circulation and …

Secondary lymphoid organs are integral to initiation and execution of adaptive immune
responses. These organs provide a setting for interactions between antigen-specific …

The production of immunoglobulin A (IgA) in mammals exceeds all other isotypes, and it is
mostly exported across mucous membranes. The discovery of IgA and the realization that it …

The members of the tumour necrosis factor (TNF)/tumour necrosis factor receptor (TNFR)
superfamily are critically involved in the maintenance of homeostasis of the immune system …