The present review summarizes recent advances in the transcriptional regulation of the
human apolipoprotein genes, focusing mostly, but not exclusively, on in-vivo studies and …

Lipid transport and ATP synthesis are critical for the progression of non-alcoholic fatty liver
disease (NAFLD), but the underlying mechanisms are largely unknown. Here, we report that …

Abstract System-wide cross-linking and immunoprecipitation (CLIP) approaches have
unveiled regulatory mechanisms of RNA-binding proteins (RBPs) mainly in cultured cells …

Apolipoprotein B is a large, amphipathic protein that plays a central role in lipoprotein
metabolism. Because its overproduction and deficiency leads to metabolic and pathologic …

Even though every cell in an organism contains the same genetic material, each cell does
not express the same cohort of genes. Therefore, one of the major problems facing genomic …

The apoA-I/C-III/A-IV gene cluster, like most intestine-specific genes, displays a specific
pattern of expression along the intestinal cephalocaudal and crypt-to-villus axes. We have …

The 5 'boundary of the chromosomal domain of the human apolipoprotein B (apoB) gene in
intestinal cells has been localized and characterized. It is composed of two kinds of …

Quercetin is one of the most abundant polyphenolic flavonoids found in fruits and
vegetables and has anti-oxidative and anti-obesity effects. Because the small intestine is a …

Publisher Summary This chapter focuses on the mechanisms by which lipoproteins are
assembled and secreted from the liver and intestine. It discusses how lipids are assembled …

C/EBPB is a crucial transcription factor, participating in a variety of biological processes
including cell proliferation, differentiation and development. In the cardiovascular system …