[HTML][HTML] VEGF/VEGFR-targeted therapy and immunotherapy in non-small cell lung cancer: targeting the tumor microenvironment

Y Zhao, S Guo, J Deng, J Shen, F Du… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is the leading cause of death by cancer worldwide.
Despite developments in therapeutic approaches for the past few decades, the 5-year …

Atherosclerosis and inflammation: Insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies

M Moradi, A Mousavi, Z Emamgholipour… - European Journal of …, 2023 - Elsevier
Angiogenesis, the formation of new blood vessels from the existing vasculature, is pivotal in
the migration, growth, and differentiation of endothelial cells in normal physiological …

[HTML][HTML] New advances in the research of clinical treatment and novel anticancer agents in tumor angiogenesis

X Li, J Zhou, X Wang, C Li, Z Ma, Q Wan… - Biomedicine & …, 2023 - Elsevier
In 1971, Folkman proposed that tumors could be limited to very small sizes by blocking
angiogenesis. Angiogenesis is the generation of new blood vessels from pre-existing …

Physiological and pathological consequences of exosomes at the blood–brain-barrier interface

L Salimi, F Seyedaghamiri, M Karimipour… - Cell Communication and …, 2023 - Springer
Blood–brain barrier (BBB) interface with multicellular structure controls strictly the entry of
varied circulating macromolecules from the blood-facing surface into the brain parenchyma …

Bioinformatics and system biological approaches for the identification of genetic risk factors in the progression of cardiovascular disease

JD Barua, SBS Omit, HK Rana… - Cardiovascular …, 2022 - Wiley Online Library
Background. Cardiovascular disease (CVD) is the combination of coronary heart disease,
myocardial infarction, rheumatic heart disease, and peripheral vascular disease of the heart …

Impaired VEGF-A-mediated neurovascular crosstalk induced by SARS-CoV-2 spike protein: a potential hypothesis explaining long COVID-19 symptoms and COVID …

R Talotta - Microorganisms, 2022 - mdpi.com
Long coronavirus disease-19 (COVID-19) is a newly discovered syndrome characterized by
multiple organ manifestations that persist for weeks to months, following the recovery from …

Fine-mapping of retinal vascular complexity loci identifies Notch regulation as a shared mechanism with myocardial infarction outcomes

A Villaplana-Velasco, M Pigeyre, J Engelmann… - Communications …, 2023 - nature.com
There is increasing evidence that the complexity of the retinal vasculature measured as
fractal dimension, Df, might offer earlier insights into the progression of coronary artery …

[HTML][HTML] Novel metal nanomaterials to promote angiogenesis in tissue regeneration

YG Yoshida, S Yan, H Xu, J Yang - Engineered regeneration, 2023 - Elsevier
Angiogenesis—the formation of new blood vessels from existing blood vessels—has drawn
significant attention in medical research. New techniques have been developed to control …

Therapeutic potential of VEGF-B in coronary heart disease and heart failure: dream or vision?

R Mallick, S Ylä-Herttuala - Cells, 2022 - mdpi.com
Coronary heart disease (CHD) is the leading cause of death around the world. Based on the
roles of vascular endothelial growth factor (VEGF) family members to regulate blood and …