An outlook on microfluidics: the promise and the challenge
S Battat, DA Weitz, GM Whitesides - Lab on a Chip, 2022 - pubs.rsc.org
This perspective considers ways in which the field of microfluidics can increase its impact by
improving existing technologies and enabling new functionalities. We highlight applications …
improving existing technologies and enabling new functionalities. We highlight applications …
[HTML][HTML] A review of current methods in microfluidic device fabrication and future commercialization prospects
Microfluidic devices currently play an important role in many biological, chemical, and
engineering applications, and there are many ways to fabricate the necessary channel and …
engineering applications, and there are many ways to fabricate the necessary channel and …
[HTML][HTML] Acoustofluidic separation of cells and particles
Acoustofluidics, the integration of acoustics and microfluidics, is a rapidly growing research
field that is addressing challenges in biology, medicine, chemistry, engineering, and …
field that is addressing challenges in biology, medicine, chemistry, engineering, and …
Autonomous discovery in the chemical sciences part I: Progress
This two‐part Review examines how automation has contributed to different aspects of
discovery in the chemical sciences. In this first part, we describe a classification for …
discovery in the chemical sciences. In this first part, we describe a classification for …
Microfluidics for drug development: from synthesis to evaluation
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …
delivery, and drug evaluation. Compared with conventional drug development procedures …
[HTML][HTML] Droplet-based high-throughput single microbe RNA sequencing by smRandom-seq
Bacteria colonize almost all parts of the human body and can differ significantly. However,
the population level transcriptomics measurements can only describe the average bacteria …
the population level transcriptomics measurements can only describe the average bacteria …
[HTML][HTML] Machine learning enables design automation of microfluidic flow-focusing droplet generation
A Lashkaripour, C Rodriguez, N Mehdipour… - Nature …, 2021 - nature.com
Droplet-based microfluidic devices hold immense potential in becoming inexpensive
alternatives to existing screening platforms across life science applications, such as enzyme …
alternatives to existing screening platforms across life science applications, such as enzyme …
Single-cell barcoding and sequencing using droplet microfluidics
Single-cell RNA sequencing has recently emerged as a powerful tool for mapping cellular
heterogeneity in diseased and healthy tissues, yet high-throughput methods are needed for …
heterogeneity in diseased and healthy tissues, yet high-throughput methods are needed for …
Ultrahigh-Throughput Enzyme Engineering and Discovery in In Vitro Compartments
Novel and improved biocatalysts are increasingly sourced from libraries via experimental
screening. The success of such campaigns is crucially dependent on the number of …
screening. The success of such campaigns is crucially dependent on the number of …
[HTML][HTML] Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells
It has long been the dream of biologists to map gene expression at the single-cell level. With
such data one might track heterogeneous cell sub-populations, and infer regulatory …
such data one might track heterogeneous cell sub-populations, and infer regulatory …