Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

Current trends in applications of circulatory microchimerism detection in transplantation

H Andrikovics, Z Őrfi, N Meggyesi, A Bors… - International Journal of …, 2019 - mdpi.com
Primarily due to recent advances of detection techniques, microchimerism (the proportion of
minor variant population is below 1%) has recently gained increasing attention in the field of …

Impact of cryopreservation and transit times of allogeneic grafts on hematopoietic and immune reconstitution

K Maurer, HT Kim, TM Kuczmarski, HM Garrity… - Blood …, 2021 - ashpublications.org
We sought to evaluate the impact of cryopreservation of unrelated donor (URD) peripheral
blood stem cell (PBSC) grafts on engraftment, chimerism, and immune reconstitution in the …

Diagnostic value of highly-sensitive chimerism analysis after allogeneic stem cell transplantation

L Sellmann, K Rabe, I Bünting, E Dammann… - Bone marrow …, 2018 - nature.com
Conventional analysis of host chimerism (HC) frequently fails to detect relapse before its
clinical manifestation in patients with hematological malignancies after allogeneic stem cell …

Short tandem repeats (STRs) as biomarkers for the quantitative follow-up of chimerism after stem cell transplantation: methodological considerations and clinical …

A Navarro-Bailón, D Carbonell, A Escudero, M Chicano… - Genes, 2020 - mdpi.com
Chimerism refers to the relative proportion of donor and recipient DNA after hematopoietic
stem cell transplantation (HSCT) and its quantitative follow-up is of great clinical utility in this …

Lineage-specific early complete donor chimerism and risk of relapse after allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia

H Lindahl, S Vonlanthen, D Valentini… - Bone Marrow …, 2022 - nature.com
Recipient–donor chimerism is routinely analyzed after allogeneic hematopoietic stem cell
transplantation (HSCT) to monitor engraftment and graft rejection. For malignancies …

[HTML][HTML] Clinical utility of quantitative PCR for chimerism and engraftment monitoring after allogeneic stem cell transplantation for hematologic malignancies

M Ahci, K Stempelmann, U Buttkereit, P Crivello… - Biology of Blood and …, 2017 - Elsevier
Although quantitative PCR (qPCR) has been explored for chimerism monitoring after
allogeneic stem cell transplantation (SCT), evidence regarding its clinical utility compared …

[HTML][HTML] Personalized chimerism test that uses selection of short tandem repeat or quantitative PCR depending on patient's chimerism status

J Tyler, L Kumer, C Fisher, H Casey, H Shike - The Journal of Molecular …, 2019 - Elsevier
Chimerism testing is used to monitor engraftment and risk of relapse after allogeneic
hematopoietic stem cell transplantation for hematologic malignancies. Although short …

Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle

A Ideta, S Yamashita, M Seki-Soma, R Yamaguchi… - Scientific Reports, 2016 - nature.com
Blastocyst complementation (BC) systems have enabled in vivo generation of organs from
allogeneic pluripotent cells, compensating for an empty germ cell niche in gene knockout …

Chimerism Testing by Next Generation Sequencing for Detection of Engraftment and Early Disease Relapse in Allogeneic Hematopoietic Cell Transplantation and an …

A Liacini, G Tripathi, A McCollick, C Gravante… - International Journal of …, 2023 - mdpi.com
Chimerism monitoring after allogenic Hematopoietic Cell Transplantation (allo-HCT) is
critical to determine how well donor cells have engrafted and to detect relapse for early …