Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a
most dramatic departure from the native structure of DNA. The present review summarizes …

The specificity and predictability of hybridization make oligonucleotides a powerful platform
to program assemblies and networks with logic-gated responses, an area of research which …

The evolution of drug resistance to many antimalarial drugs in the lethal strain of malaria
(Plasmodium falciparum) has been a great concern over the past 50 years. Among these …

We have developed a new class of triplex-forming peptide nucleic acid (PNA)-based
fluorogenic probes for sensing of the panhandle structure of the influenza A virus (IAV) RNA …

RNAs form secondary structures containing double‐stranded base paired regions and
single‐stranded regions. Probing, detecting and modulating RNA structures and dynamics …

In order to overcome the pH limitations of triplex-forming peptide nucleic acid (PNA) in
binding to double-stranded RNA (dsRNA), we have recently proposed a new design of …

Nucleic acid represents the ideal drug candidate for protein targets that are hard to target or
against which drug development is not easy. Peptide nucleic acids (PNAs) are synthesized …

Four new isoorotamide (Io)‐containing PNA nucleobases have been designed for A− U
recognition of double helical RNA. New PNA monomers were prepared efficiently and …

Chemically modified short peptide nucleic acids (PNAs) recognize RNA duplexes under
near physiological conditions by major-groove PNA· RNA–RNA triplex formation and show …

Efficient detection and observation of dynamic RNA changes remain a tremendous
challenge. However, the continuous development of fluorescence applications in recent …