Epidemiology and treatment of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa infections

JP Horcajada, M Montero, A Oliver, L Sorlí… - Clinical microbiology …, 2019 - Am Soc Microbiol
In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

Multidrug-resistant bacteria in the community: trends and lessons learned

D Van Duin, DL Paterson - Infectious disease clinics, 2016 - id.theclinics.com
Multidrug resistant (MDR) bacteria are well-recognized to be one of the most important
current public health problems. The Infectious Diseases Society of America recognizes …

[HTML][HTML] Increased detection of carbapenemase-producing Enterobacterales bacteria in Latin America and the Caribbean during the COVID-19 pandemic

GR Thomas, A Corso, F Pasterán, J Shal… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
Abstract During 2020–2021, countries in Latin America and the Caribbean reported clinical
emergence of carbapenemase-producing Enterobacterales that had not been previously …

[HTML][HTML] Systematic review and meta-analysis of mortality of patients infected with carbapenem-resistant Klebsiella pneumoniae

L Xu, X Sun, X Ma - Annals of clinical microbiology and antimicrobials, 2017 - Springer
Purpose Carbapenem resistant K. pneumoniae (CRKP) has aroused widespread attention
owing to its very limited therapeutic options, and this strain has increased rapidly in recent …

Multidrug‐resistant bacteria: their mechanism of action and prophylaxis

A Bharadwaj, A Rastogi, S Pandey… - BioMed research …, 2022 - Wiley Online Library
In the present scenario, resistance to antibiotics is one of the crucial issues related to public
health. Earlier, such resistance to antibiotics was limited to nosocomial infections, but it has …

Betulin and its derivatives as novel compounds with different pharmacological effects

S Amiri, S Dastghaib, M Ahmadi, P Mehrbod… - Biotechnology …, 2020 - Elsevier
Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids
which possess a wide range of pharmacological activities. Recent evidence indicates that B …

[HTML][HTML] Deaths attributable to carbapenem-resistant Enterobacteriaceae infections

ME Falagas, GS Tansarli… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
We evaluated the number of deaths attributable to carbapenem-resistant
Enterobacteriaceae by using studies from around the world published before April 9, 2012 …

[HTML][HTML] An international multicenter retrospective study of Pseudomonas aeruginosa nosocomial pneumonia: impact of multidrug resistance

ST Micek, RG Wunderink, MH Kollef, C Chen, J Rello… - Critical Care, 2015 - Springer
Introduction Pseudomonas aeruginosa nosocomial pneumonia (Pa-NP) is associated with
considerable morbidity, prolonged hospitalization, increased costs, and mortality. Methods …

Phage therapy efficacy: a review of the last 10 years of preclinical studies

LDR Melo, H Oliveira, DP Pires… - Critical reviews in …, 2020 - Taylor & Francis
Due to the rise of multidrug-resistant infections in humans, phage therapy is gaining
renewed attention in Western medicine. Despite the increasing number of publications …

Impact on morbidity, mortality, and length of stay of hospital-acquired infections by resistant microorganisms

JI Barrasa-Villar, C Aibar-Remón… - Clinical Infectious …, 2017 - academic.oup.com
Background Infections by multidrug-resistant organisms (MDROs) are a global threat and
are particularly common in hospitals. This study was performed to assess the impact of …