The current state and future directions of skeletal toxicology: Forensic and humanitarian implications of a proposed model for the in vivo incorporation of drugs into the …

KM Rubin - Forensic science international, 2018 - Elsevier
At present, the inability to meaningfully and reliably conduct toxicological testing on human
skeletal material represents a significant gap in forensic practice, especially in a time when …

A review of multi-disciplinary decomposition research and key drivers of variation in decay

DB McIntyre, BM Dawson, BM Long… - International journal of …, 2024 - Springer
The decomposition of animal remains is a multifaceted process, involving ecological,
biological, and chemical interactions. While the complexity is acknowledged through …

Chemical composition effect on latent print development using black fingerprint powders

S Moreno, G Brown, M Klein, Q Wang, JT Markiewicz… - Forensic Chemistry, 2021 - Elsevier
Fingerprint development has been used to visualize latent prints since the 19th century, and
several companies produce a variety of commercially available black fingerprint powders …

Development and validation of a gas chromatography–mass spectrometry method for opiates and cocaine in human bone

L Fernandez-Lopez, A Luna-Maldonado… - … of Pharmaceutical and …, 2019 - Elsevier
A method based on gas chromatography–mass spectrometry (GC–MS) is described for the
determination of opioids (6-monoacetylmorphine, morphine, methadone and tramadol) and …

Distribution of methadone and metabolites in skeletal tissue

M Vandenbosch, T Somers… - Journal of Analytical …, 2018 - academic.oup.com
In forensic toxicology, when extended time has elapsed before discovery of the body, the
most commonly analyzed specimens are often degraded or not available at all due to …

Comparison of relative distribution of ketamine and norketamine in decomposed skeletal tissues following single and repeated exposures

JH Watterson, JP Donohue… - Journal of Analytical …, 2012 - academic.oup.com
Bone was analyzed for ketamine and norketamine to examine whether different patterns of
drug exposure could be discriminated. Rats received (intraperitoneally) one 75 mg/kg dose …

Relative distribution of ketamine and norketamine in skeletal tissues following various periods of decomposition

JH Watterson, JP Donohue - Journal of Analytical Toxicology, 2011 - academic.oup.com
Skeletal tissues (rat) were analyzed for ketamine (KET) and norketamine (NKET) following
acute ketamine exposure (75 mg/kg ip) to examine the influence of bone type and …

Development and validation of a method for analysing of duloxetine, venlafaxine and amitriptyline in human bone

L Fernandez-Lopez, M Pellegrini, MC Rotolo… - Forensic science …, 2019 - Elsevier
A method based on gas chromatography–mass spectrometry (GC–MS) is described for the
determination of venlafaxine, amitriptyline and duloxetine in human bone. Pulverized …

Discrimination between patterns of drug exposure by toxicological analysis of decomposed skeletal tissues. Part II: amitriptyline and citalopram

JH Watterson, HM Cornthwaite - Journal of Analytical …, 2013 - academic.oup.com
Decomposed bone and plasma samples of rats exposed to amitriptyline (AMI) and
citalopram (CIT) under different dosing patterns were analyzed. Wistar rats received one …

Postmortem analysis of opioids and metabolites in skeletal tissue

M Vandenbosch, S Pajk… - Journal of Analytical …, 2022 - academic.oup.com
Every year, thousands of suspicious deaths are accounted for by an overdose of opioids.
Occasionally all traditional matrices are unavailable due to decomposition. Skeletal tissue …