Stress and the dopaminergic reward system

JH Baik - Experimental & molecular medicine, 2020 - nature.com
Dopamine regulates reward-related behavior through the mesolimbic dopaminergic
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …

Neurobiologic advances from the brain disease model of addiction

ND Volkow, GF Koob, AT McLellan - New England Journal of …, 2016 - Mass Medical Soc
Neurobiologic Advances from the Brain Disease Model of Addiction | NEJM Skip to main content
NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …

Decoding molecular and cellular heterogeneity of mouse nucleus accumbens

R Chen, TR Blosser, MN Djekidel, J Hao… - Nature …, 2021 - nature.com
The nucleus accumbens (NAc) plays an important role in regulating multiple behaviors, and
its dysfunction has been linked to many neural disorders. However, the molecular, cellular …

[PDF][PDF] The brain on drugs: from reward to addiction

ND Volkow, M Morales - Cell, 2015 - cell.com
Advances in neuroscience identified addiction as a chronic brain disease with strong
genetic, neurodevelopmental, and sociocultural components. We here discuss the circuit …

Neuroscience of addiction: relevance to prevention and treatment

ND Volkow, M Boyle - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
Addiction, the most severe form of substance use disorder, is a chronic brain disorder
molded by strong biosocial factors that has devastating consequences to individuals and to …

Ventral tegmental area GABAergic inhibition of cholinergic interneurons in the ventral nucleus accumbens shell promotes reward reinforcement

R Al-Hasani, R Gowrishankar, GP Schmitz… - Nature …, 2021 - nature.com
The long-range GABAergic input from the ventral tegmental area (VTA) to the nucleus
accumbens (NAc) is relatively understudied, and therefore its role in reward processing has …

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

Internet gaming addiction: current perspectives

DJ Kuss - Psychology research and behavior management, 2013 - Taylor & Francis
In the 2000s, online games became popular, while studies of Internet gaming addiction
emerged, outlining the negative consequences of excessive gaming, its prevalence, and …

[PDF][PDF] Dopamine in motivational control: rewarding, aversive, and alerting

ES Bromberg-Martin, M Matsumoto, O Hikosaka - Neuron, 2010 - cell.com
Midbrain dopamine neurons are well known for their strong responses to rewards and their
critical role in positive motivation. It has become increasingly clear, however, that dopamine …

[PDF][PDF] Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens

JP Britt, F Benaliouad, RA McDevitt, GD Stuber… - Neuron, 2012 - cell.com
Excitatory afferents to the nucleus accumbens (NAc) are thought to facilitate reward seeking
by encoding reward-associated cues. Selective activation of different glutamatergic inputs to …