The obesity epidemic has been widely publicized in the media worldwide. Investigators at all
levels have been looking for factors that have contributed to the development of this …

The involvement of dopamine within the nucleus accumbens in the formation and
maintenance of pair bonds was assessed in a series of experiments using the monogamous …

Dopamine neurons of the ventral tegmental area (VTA) regulate reward association and
motivation. It remains unclear whether there are distinct dopamine populations to mediate …

A major hurdle in defining the molecular biology of nicotine addiction has been
characterizing the different nicotinic acetylcholine receptor (nAChR) subtypes in the brain …

Addiction is a chronic, relapsing disorder, characterised by the long-term propensity of
addicted individuals to relapse. A major factor that obstructs the attainment of abstinence is …

Chronic vulnerability to relapse is a formidable challenge for the treatment of drug addiction.
The neurobiological basis of relapse and its prevention has, therefore, attracted major …

Flow is a state of full task absorption, accompanied with a strong drive and low levels of self‐
referential thinking. Flow is likely when there is a match between a person's skills and the …

The multifaceted concept of impulsivity implies that different impulsivity aspects, mediated by
different neural processes, influence behavior at different levels. The nucleus accumbens …

Midbrain dopamine neurons fire in bursts conveying salient information. Bursts are
associated with pauses in tonic firing of striatal cholinergic interneurons. Although the …

According to the dopamine (DA) hypothesis of reward, DA systems in the brain, particularly
in the nucleus accumbens, are thought to directly mediate the rewarding or primary …