Identifying the neural circuitry of alcohol craving and relapse vulnerability
With no further intervention, relapse rates in detoxified alcoholics are high and usually
exceed 80% of all detoxified patients. It has been suggested that stress and exposure to …
exceed 80% of all detoxified patients. It has been suggested that stress and exposure to …
The nucleus accumbens as part of a basal ganglia action selection circuit
SM Nicola - Psychopharmacology, 2007 - Springer
Background The nucleus accumbens is the ventral extent of the striatum, the main input
nucleus of the basal ganglia. Recent hypotheses propose that the accumbens and its …
nucleus of the basal ganglia. Recent hypotheses propose that the accumbens and its …
Rewarding properties of social interactions in adolescent and adult male and female rats: impact of social versus isolate housing of subjects and partners
LA Douglas, EI Varlinskaya… - … : The Journal of the …, 2004 - Wiley Online Library
Social interactions have been shown to be rewarding for adolescent and adult rats;
however, there has been little emphasis on comparing the strength of the rewarding value of …
however, there has been little emphasis on comparing the strength of the rewarding value of …
The limbic lobe and its output channels: implications for emotional functions and adaptive behavior
L Heimer, GW Van Hoesen - Neuroscience & Biobehavioral Reviews, 2006 - Elsevier
Current dissatisfaction with the limbic system concept reflects a desire to move beyond the
limbic system in efforts to explain key facets of emotional functions and motivational …
limbic system in efforts to explain key facets of emotional functions and motivational …
Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons
R Saba, PH Störchel, A Aksoy-Aksel… - … and cellular biology, 2012 - Taylor & Francis
The dynamic expression of AMPA-type glutamate receptors (AMPA-R) at synapses is a key
determinant of synaptic plasticity, including neuroadaptations to drugs of abuse. Recently …
determinant of synaptic plasticity, including neuroadaptations to drugs of abuse. Recently …
The dopamine hypothesis of drug addiction: hypodopaminergic state
Drug addiction is a brain disorder caused by the repetitive use of various chemicals which
alter normal functioning of the central nervous system with consequent behavioral …
alter normal functioning of the central nervous system with consequent behavioral …
The role of the striatum in aversive learning and aversive prediction errors
Neuroeconomic studies of decision making have emphasized reward learning as critical in
the representation of value-driven choice behaviour. However, it is readily apparent that …
the representation of value-driven choice behaviour. However, it is readily apparent that …
A systematic review of fMRI reward paradigms used in studies of adolescents vs. adults: the impact of task design and implications for understanding …
The neural systems underlying reward-related behaviors across development have recently
generated a great amount of interest. Yet, the neurodevelopmental literature on reward …
generated a great amount of interest. Yet, the neurodevelopmental literature on reward …
Acetylcholine–dopamine interactions in the pathophysiology and treatment of CNS disorders
Dopaminergic neurons in the substantia nigra pars compacta and ventral tegmental area of
the midbrain form the nigrostriatal and mesocorticolimbic dopaminergic pathways that …
the midbrain form the nigrostriatal and mesocorticolimbic dopaminergic pathways that …
[HTML][HTML] Glutamatergic transmission in drug reward: implications for drug addiction
MS D'Souza - Frontiers in neuroscience, 2015 - frontiersin.org
Individuals addicted to drugs of abuse such as alcohol, nicotine, cocaine, and heroin are a
significant burden on healthcare systems all over the world. The positive reinforcing …
significant burden on healthcare systems all over the world. The positive reinforcing …