[HTML][HTML] Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
[HTML][HTML] Fatigue, sleep, and autoimmune and related disorders
MR Zielinski, DM Systrom, NR Rose - Frontiers in immunology, 2019 - frontiersin.org
Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …
Molecular mechanisms and cellular events involved in the neuroprotective actions of estradiol. Analysis of sex differences
I Azcoitia, GE Barreto, LM Garcia-Segura - Frontiers in neuroendocrinology, 2019 - Elsevier
Estradiol, either from peripheral or central origin, activates multiple molecular
neuroprotective and neuroreparative responses that, being mediated by estrogen receptors …
neuroprotective and neuroreparative responses that, being mediated by estrogen receptors …
[HTML][HTML] The role of autophagy in acute myocardial infarction
D Wu, K Zhang, P Hu - Frontiers in pharmacology, 2019 - frontiersin.org
Acute myocardial infarction refers to a sudden death of cardiomyocytes, which leads to a
large mortality worldwide. To attenuate acute myocardial infarction, strategies should be …
large mortality worldwide. To attenuate acute myocardial infarction, strategies should be …
[HTML][HTML] Inhibition of PDE1-B by vinpocetine regulates microglial exosomes and polarization through enhancing autophagic flux for neuroprotection against ischemic …
J Zang, Y Wu, X Su, T Zhang, X Tang, D Ma… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes contribute to cell–cell communications. Emerging evidence has shown that
microglial exosomes may play crucial role in regulation of neuronal functions under …
microglial exosomes may play crucial role in regulation of neuronal functions under …
Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015–2021)
P Oleksak, E Nepovimova, Z Chrienova… - European Journal of …, 2022 - Elsevier
Mechanistic target of rapamycin (mTOR) is a highly conserved protein kinase acting as a
central regulator of cell functions. The kinase forms two distinct mTOR complexes termed as …
central regulator of cell functions. The kinase forms two distinct mTOR complexes termed as …
Immune cells after ischemic stroke onset: roles, migration, and target intervention
L Ao, YY Yan, L Zhou, C Li, WT Li, W Fang… - Journal of Molecular …, 2018 - Springer
Ischemic stroke is one of the leading health issues and the major cause of permanent
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …
disability in adults worldwide. Energy depletion and hypoxia occurring after ischemic stroke …
[HTML][HTML] The role of estradiol in traumatic brain injury: mechanism and treatment potential
Patients surviving traumatic brain injury (TBI) face numerous neurological and
neuropsychological problems significantly affecting their quality of life. Extensive studies …
neuropsychological problems significantly affecting their quality of life. Extensive studies …
[HTML][HTML] Translation regulation by eIF2α phosphorylation and mTORC1 signaling pathways in non-communicable diseases (NCDs)
Non-communicable diseases (NCDs) are medical conditions that, by definition, are non-
infectious and non-transmissible among people. Much of current NCDs are generally due to …
infectious and non-transmissible among people. Much of current NCDs are generally due to …
Neuroprotective effects of VEGF-A nanofiber membrane and FAAH Inhibitor URB597 against oxygen–glucose deprivation-induced ischemic neuronal injury
DP Wang, KY Jin, P Zhao, Q Lin, K Kang… - International journal of …, 2021 - Taylor & Francis
Introduction Brain ischemia is a common neurological disorder worldwide that activates a
cascade of pathophysiological events involving decreases in oxygen and glucose levels …
cascade of pathophysiological events involving decreases in oxygen and glucose levels …