Antitumor mechanisms of molecules secreted by Trypanosoma cruzi in colon and breast cancer: A review

S Sadr, S Ghiassi, N Lotfalizadeh… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Background: Molecules secreted by Trypanosoma cruzi (T. cruzi) have beneficial effects on
the immune system and can fight against cancer by inhibiting the growth of tumor cells …

Molecular and clinical aspects of chronic manifestations in Chagas disease: a state-of-the-art review

GJ Medina-Rincón, S Gallo-Bernal, PA Jiménez… - Pathogens, 2021 - mdpi.com
Chronic manifestations of Chagas disease present as disabling and life-threatening
conditions affecting mainly the cardiovascular and gastrointestinal systems. Although …

The transcriptome landscape of 3D-cultured placental trophoblasts reveals activation of TLR2 and TLR3/7 in response to low Trypanosoma cruzi parasite exposure

E Silberstein, CC Chung, A Debrabant - Frontiers in Microbiology, 2023 - frontiersin.org
Vertical transmission of Trypanosoma cruzi (T. cruzi) become a globalized health problem
accounting for 22% of new cases of Chagas disease (CD). Congenital infection is now …

Comparative microRNA profiling of Trypanosoma cruzi infected human cells

N Rego, MG Libisch, C Rovira, JP Tosar… - Frontiers in cellular and …, 2023 - frontiersin.org
Introduction Trypanosoma cruzi, the causative agent of Chagas disease, can infect almost
any nucleated cell in the mammalian host. Although previous studies have described the …

Plasmodium's fight for survival: escaping elimination while acquiring nutrients

EA Schroeder, ME Chirgwin, ER Derbyshire - Trends in parasitology, 2022 - cell.com
Plasmodium parasites extensively alter their host hepatocyte to evade host detection and
support an unprecedented replication rate. Host cell manipulation includes association with …

Interaction between peripheral blood mononuclear cells and Trypanosoma cruzi-infected adipocytes: implications for treatment failure and induction of …

LR Moreira, AC Silva, CN Costa-Oliveira… - Frontiers in …, 2024 - frontiersin.org
Background/Introduction Adipose tissue (AT) has been highlighted as a promising reservoir
of infection for viruses, bacteria and parasites. Among them is Trypanosoma cruzi, which …

Omics data integration facilitates target selection for new antiparasitic drugs against TriTryp infections

M Rivara-Espasandín, MC Palumbo, EJ Sosa… - Frontiers in …, 2023 - frontiersin.org
Introduction: Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp., commonly
referred to as TriTryps, are a group of protozoan parasites that cause important human …

Unique endomembrane systems and virulence in pathogenic protozoa

MF Wiser - Life, 2021 - mdpi.com
Virulence in pathogenic protozoa is often tied to secretory processes such as the expression
of adhesins on parasite surfaces or the secretion of proteases to assisted in tissue invasion …

Galectins in Chagas Disease: A Missing Link Between Trypanosoma cruzi Infection, Inflammation, and Tissue Damage

CV Poncini, AF Benatar, KA Gomez… - Frontiers in …, 2022 - frontiersin.org
Trypanosoma cruzi, the protozoan parasite causative agent of Chagas disease, affects
about seven million people worldwide, representing a major global public health concern …

Trypanin Disruption Affects the Motility and Infectivity of the Protozoan Trypanosoma cruzi

JL Saenz-Garcia, BS Borges, N Souza-Melo… - Frontiers in Cellular …, 2022 - frontiersin.org
The flagellum of Trypanosomatids is an organelle that contributes to multiple functions,
including motility, cell division, and host–pathogen interaction. Trypanin was first described …