Despite the well-known sex dimorphism in cardiovascular disease traits, the exact genetic,
molecular, and cellular underpinnings of these differences are not well understood. A …

The pathogenesis of obesity-associated cardiovascular diseases begins long prior to the
presentation of a cardiovascular event. In both men and women, cardiovascular events, and …

Context The relation between the menopause transition (MT) and changes in regional fat
distribution is uncertain. Objective To determine whether the MT is associated with the …

Ovarian reserve is a term used to estimate the total number of immature follicles present in
the ovaries. Between birth and menopause, there is a progressive decrease in the number …

Background Osteoporosis is a disease threatening the health of millions of individuals.
Melatonin is found to be a potential anti-osteoporosis drug. However, whether melatonin …

Ovarian aging occurs prior to the aging of other organ systems and acts as the pacemaker of
the aging process of multiple organs. As life expectancy has increased, preventing ovarian …

Aging is an important risk factor for the development of heart failure (HF) and half of patients
with HF have preserved ejection fraction (HFpEF) which is more common in elderly women …

The decrease in ovarian hormone secretion that occurs during menopause results in an
increase in body weight and adipose tissue mass. Probiotics and soy isoflavones (SIFs) …

Aims Roflumilast, a well-known phosphodiesterase-4 (PDE-4) inhibitor, possess an anti-
inflammatory activity with approved indications in chronic obstructive pulmonary disease …

Background Accumulation of bone marrow adipose tissue (BMAT) is always seen in
osteoporosis induced by estrogen deficiency. Herein, we aimed to investigate the …