Organic photosensitizers for antimicrobial phototherapy

VN Nguyen, Z Zhao, BZ Tang, J Yoon - Chemical Society Reviews, 2022 - pubs.rsc.org
Microbial infectious diseases, especially those caused by new and antibiotic-resistant
pathogenic microbes, have become a significant threat to global human health. As an …

Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy

KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …

Rational design of biomaterials to potentiate cancer thermal therapy

Y Zhu, Q Li, C Wang, Y Hao, N Yang, M Chen… - Chemical …, 2023 - ACS Publications
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023 - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Integration of TADF photosensitizer as “electron pump” and BSA as “electron reservoir” for boosting type I photodynamic therapy

W Chen, Z Wang, M Tian, G Hong, Y Wu… - Journal of the …, 2023 - ACS Publications
Type I photosensitization provides an effective solution to the problem of unsatisfactory
photodynamic therapeutic (PDT) effects caused by the tumor hypoxia. The challenge in the …

Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H Xiong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …

Mitochondria-targeted smart AIEgens: Imaging and therapeutics

H Li, H Kim, C Zhang, S Zeng, Q Chen, L Jia… - Coordination Chemistry …, 2022 - Elsevier
Mitochondria are not only the main energy source of the cell but are also involved in the
regulation of important physiology and processes of diseases including cancers. Therefore …

[HTML][HTML] Theranostic imaging and multimodal photodynamic therapy and immunotherapy using the mTOR signaling pathway

H Zhou, D Tang, Y Yu, L Zhang, B Wang… - Nature …, 2023 - nature.com
Tumor metastases are considered the leading cause of cancer-associated deaths. While
clinically applied drugs have demonstrated to efficiently remove the primary tumor …

Self-assembled metallacage with second near-infrared aggregation-induced emission for enhanced multimodal theranostics

Y Qin, X Chen, Y Gui, H Wang, BZ Tang… - Journal of the American …, 2022 - ACS Publications
The construction of supramolecular coordination complexes (SCCs) featuring prominent
cancer theranostic functions is an appealing yet significantly challenging task. In this study …