The autoimmune bases of infertility and pregnancy loss

HJA Carp, C Selmi, Y Shoenfeld - Journal of autoimmunity, 2012 - Elsevier
Several lines of evidence suggest that autoimmune mechanisms may influence the
reproductive life and fertility of both sexes, commonly manifesting as infertility or pregnancy …

Antiphospholipid antibodies in women with recurrent embryo implantation failure: A systematic review and meta-analysis

M Jarne-Borràs, F Miró-Mur, A Anunciación-Llunell… - Autoimmunity …, 2022 - Elsevier
Objective Antiphospholipid antibodies (aPL) are related to poor pregnancy outcomes, but
their effect on embryo implantation is unclear. We aimed to assess the prevalence of …

Functional endometrial polyps in infertile asymptomatic patients: a possible evolution of vascular changes secondary to endometritis

FM Carvalho, FN Aguiar, R Tomioka… - European Journal of …, 2013 - Elsevier
Objective Functional polyps and chronic endometritis are among the most common
abnormalities seen in the endometrium of patients with implantation failures and recurrent …

Obstetric antiphospholipid syndrome: a recent classification for an old defined disorder

S D'Ippolito, PL Meroni, T Koike, M Veglia… - Autoimmunity …, 2014 - Elsevier
Obstetric antiphospholipid syndrome (APS) is now being recognized as a distinct entity from
vascular APS. Pregnancy morbidity includes> 3 consecutive and spontaneous early …

ApoE receptor 2 mediation of trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice

V Ulrich, SE Gelber, M Vukelic… - Arthritis & …, 2016 - Wiley Online Library
Objective Pregnancies in women with the antiphospholipid syndrome (APS) are frequently
complicated by fetal loss and intrauterine growth restriction (IUGR). How circulating …

Pregnancy and autoimmunity: a common problem

C Perricone, C de Carolis, R Perricone - Best Practice & Research Clinical …, 2012 - Elsevier
Successful pregnancy is considered a Th1–Th2 cooperation phenomenon (Th, T-helper),
with a predominantly Th2-type lymphocytes response, together with the emerging role of …

Safety issues and recommendations for successful pregnancy outcome in systemic lupus erythematosus

SK Nahal, C Selmi, ME Gershwin - Journal of Autoimmunity, 2018 - Elsevier
Systemic lupus erythematosus (SLE) primarily affects women of childbearing age. One of the
major changes in SLE focuses on the timing of a successful pregnancy. In the past …

Anti‐phosphatidylserine/prothrombin antibodies are associated with adverse pregnancy outcomes

P Žigon, K Perdan Pirkmajer, M Tomšič… - Journal of …, 2015 - Wiley Online Library
Objective. To determine the prevalence and clinical association of anti‐phosphatidylserine/
prothrombin antibodies (aPS/PT) in patients with a history of pregnancy complications …

[HTML][HTML] Loss of maternal annexin A5 increases the likelihood of placental platelet thrombosis and foetal loss

H Ueki, T Mizushina, T Laoharatchatathanin… - Scientific Reports, 2012 - nature.com
Antiphospholipid syndrome is associated with an increased risk of thrombosis and
pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however …

B-cell directed therapies in antiphospholipid antibody syndrome—new directions based on murine and human data

S Khattri, G Zandman-Goddard, E Peeva - Autoimmunity reviews, 2012 - Elsevier
The increased awareness of the role of humoral immunophysiology in antiphospholipid
syndrome (APS) has aroused interest in B cells as therapeutic targets in this disease. This …