[HTML][HTML] The adipokine network in rheumatic joint diseases

M Carrión, KW Frommer, S Pérez-García… - International journal of …, 2019 - mdpi.com
Rheumatic diseases encompass a diverse group of chronic disorders that commonly affect
musculoskeletal structures. Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two …

[HTML][HTML] Role of adiponectin in the pathogenesis of rheumatoid arthritis

K Szumilas, P Szumilas… - International journal of …, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a systemic chronic inflammatory autoimmune joint disease,
characterized by progressive articular damage and joint dysfunction. One of the symptoms of …

[HTML][HTML] Immunomodulatory effect of a very-low-calorie ketogenic diet compared with bariatric surgery and a low-calorie diet in patients with excessive body weight

PM Lorenzo, I Sajoux, AG Izquierdo… - Clinical Nutrition, 2022 - Elsevier
Background & aim Inflammation and oxidative stress are the most probable mechanistic link
between obesity and its co-diseases with cancer among them. The aim of this study was to …

[HTML][HTML] Research of pathogenesis and novel therapeutics in arthritis

CH Tang - International journal of molecular sciences, 2019 - mdpi.com
Arthritis has a high prevalence globally and includes over 100 types, the most common of
which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis and inflammatory arthritis. The …

[HTML][HTML] Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats

L Jiang, K Xu, J Li, X Zhou, L Xu, Z Wu, C Ma… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a chronic degenerative joint disease, related to the overexpression of
matrix metalloproteinases (MMPs), a disintegrin and metalloproteinase with thrombospondin …

Effect of leptin on chronic inflammatory disorders: insights to therapeutic target to prevent further cardiovascular complication

G Dessie, B Ayelign, Y Akalu, T Shibabaw… - … Syndrome and Obesity, 2021 - Taylor & Francis
In response to obesity-associated chronic inflammatory disorders, adipose tissue releases a
biologically active peptide known as leptin. Leptin activates the secretion of chemical …

[HTML][HTML] Omentin-1 ameliorates the progress of osteoarthritis by promoting IL-4-dependent anti-inflammatory responses and M2 macrophage polarization

CY Ko, YY Lin, D Achudhan, JW Chang… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent joint disease commonly associated with aging and obesity,
which can lead to pain, stiffness, joint dysfunction, and disability. Omentin-1 (also called …

[HTML][HTML] Visfatin increases VEGF-dependent angiogenesis of endothelial progenitor cells during osteoarthritis progression

CH Tsai, SC Liu, WH Chung, SW Wang, MH Wu… - Cells, 2020 - mdpi.com
Osteoarthritis (OA) pannus contains a network of neovascularization that is formed and
maintained by angiogenesis, which is promoted by vascular endothelial growth factor …

[HTML][HTML] Association between weight-adjusted-waist index and the prevalence of rheumatoid arthritis and osteoarthritis: a population-based study

X Wang, L Xie, S Yang - BMC Musculoskeletal Disorders, 2023 - Springer
Introduction The weight-adjusted-waist Index (WWI), an innovative metric for assessing
obesity, exhibits superior efficacy in appraising lean muscle and adipose tissue mass …

[HTML][HTML] Effects of tocilizumab, an anti-interleukin-6 receptor antibody, on serum lipid and adipokine levels in patients with rheumatoid arthritis

E Hoffman, MA Rahat, J Feld, M Elias, I Rosner… - International Journal of …, 2019 - mdpi.com
Patients with rheumatoid arthritis (RA) are at increased risk of cardiovascular disease.
Dyslipidemia is a known adverse effect of tocilizumab (TCZ), an anti-interleukin-6 receptor …